Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MF614_RS09530 Genome accession   NZ_CP092252
Coordinates   1947695..1948351 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ISHS7     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1942695..1953351
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MF614_RS09500 (MF614_09500) dcyD 1943575..1944561 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  MF614_RS09505 (MF614_09505) tcyL 1944576..1945244 (+) 669 WP_001158212.1 cystine ABC transporter permease -
  MF614_RS09510 (MF614_09510) tcyN 1945241..1945993 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MF614_RS09515 (MF614_09515) sdiA 1946223..1946945 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  MF614_RS09520 (MF614_09520) yecF 1947012..1947236 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  MF614_RS09525 (MF614_09525) yecU 1947223..1947399 (-) 177 WP_001326718.1 protein YecU -
  MF614_RS24605 - 1947482..1947553 (-) 72 Protein_1868 transcriptional regulator -
  MF614_RS09530 (MF614_09530) letA 1947695..1948351 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MF614_RS09535 (MF614_09535) uvrC 1948348..1950180 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  MF614_RS09540 (MF614_09540) pgsA 1950237..1950785 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MF614_RS09560 (MF614_09560) yecA 1951435..1952100 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=564896 MF614_RS09530 WP_000611335.1 1947695..1948351(+) (letA) [Escherichia coli strain ISHS7]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=564896 MF614_RS09530 WP_000611335.1 1947695..1948351(+) (letA) [Escherichia coli strain ISHS7]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486