Detailed information NTG0564528

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: MCS25_RS01925
• Genome accession: NZ_CP092048
• Coordinates: 458750..459418 (-)
• Length: 222 a.a.
• NCBI ID: WP_010956008.1
• Uniprot ID: A0A099WVY9
• Organism: Porphyromonas gingivalis strain W50
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 453750..464418

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MCS25_RS01910 (MCS25_01910)	-	453803..455185 (-)	1383	WP_010956007.1	peptidylprolyl isomerase	-
MCS25_RS01915 (MCS25_01915)	recQ	455222..457399 (-)	2178	WP_004584941.1	DNA helicase RecQ	-
MCS25_RS01920 (MCS25_01920)	clpX	457478..458713 (-)	1236	WP_005873798.1	ATP-dependent Clp protease ATP-binding subunit ClpX	-
MCS25_RS01925 (MCS25_01925)	clpP	458750..459418 (-)	669	WP_010956008.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
MCS25_RS01930 (MCS25_01930)	-	459791..460651 (-)	861	WP_005873813.1	head GIN domain-containing protein	-
MCS25_RS01935 (MCS25_01935)	-	460925..461782 (-)	858	WP_004584946.1	head GIN domain-containing protein	-
MCS25_RS01940 (MCS25_01940)	-	462288..462632 (+)	345	WP_012458362.1	hypothetical protein	-
MCS25_RS01945 (MCS25_01945)	-	462613..463272 (+)	660	WP_004584949.1	YiiX/YebB-like N1pC/P60 family cysteine hydrolase	-
MCS25_RS01950 (MCS25_01950)	-	463308..464180 (-)	873	WP_043876397.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 222 a.a.
• Molecular weight: 24804.44 Da
• Isoelectric Point: 5.6830

>NTDB_id=564528 MCS25_RS01925 WP_010956008.1 458750..459418(-) (clpP) [Porphyromonas gingivalis strain W50]
MNEFKKYATRHIGLNAQALDDYTRIQSSYISPTIIEERQLNVAQMDVFSRLMMDRIIFLGTQIDDYTANVIQAQLLYLDS
ADPGKDISIYLNSPGGSVYAGYGIYDTMQYIGCDVATICTGMAASMASVLLVAGTKGKRFALPHSRVMIHQPLGGMQGQA
SDLEIAAREILRVKKELYTIISSHSGKPVEQVEKDSDRDYWMTAPEALEYGMIDKILEKNRK

Nucleotide

• Length: 669 bp

>NTDB_id=564528 MCS25_RS01925 WP_010956008.1 458750..459418(-) (clpP) [Porphyromonas gingivalis strain W50]
ATGAACGAATTCAAAAAATACGCGACCCGACATATCGGGTTGAATGCACAGGCCTTGGACGACTATACCAGAATCCAAAG
CAGCTACATCTCTCCGACCATTATCGAAGAACGCCAGTTGAACGTTGCACAAATGGATGTGTTCTCACGTCTAATGATGG
ATCGGATCATCTTCCTTGGCACTCAGATCGACGATTACACGGCCAATGTCATTCAAGCACAGCTTCTTTATCTTGATAGC
GCCGACCCCGGTAAAGATATTTCCATCTATCTGAATTCACCCGGCGGATCTGTTTATGCCGGTTATGGCATATACGATAC
GATGCAGTATATAGGGTGCGATGTGGCCACTATCTGTACGGGCATGGCTGCGTCTATGGCATCAGTGCTGCTCGTAGCAG
GAACGAAAGGCAAACGCTTTGCTTTGCCTCATTCCCGCGTGATGATACATCAGCCGCTTGGTGGTATGCAGGGGCAGGCC
AGCGATTTGGAGATCGCAGCTCGCGAGATTCTGCGCGTCAAGAAAGAGCTTTACACGATTATCTCTTCTCACAGTGGAAA
GCCCGTCGAGCAGGTCGAAAAAGATAGTGATCGGGACTATTGGATGACAGCCCCCGAAGCATTGGAGTACGGGATGATAG
ATAAAATCCTCGAAAAGAATCGAAAGTAG

Domains

Predicted by InterProScan.

• Clp protease (CLP_protease) (44-219)

3D structure

• AlphaFold DB: A0A099WVY9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	57.527	83.784	0.482
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	53.927	86.036	0.464
clpP	Lactococcus lactis subsp. cremoris KW2	50	87.387	0.437
clpP	Streptococcus mutans UA159	49.738	86.036	0.428
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	48.454	87.387	0.423
clpP	Streptococcus thermophilus LMG 18311	48.958	86.486	0.423
clpP	Streptococcus thermophilus LMD-9	48.958	86.486	0.423
clpP	Streptococcus pyogenes MGAS315	48.691	86.036	0.419
clpP	Streptococcus pyogenes JRS4	48.691	86.036	0.419
clpP	Streptococcus pneumoniae Rx1	47.644	86.036	0.41
clpP	Streptococcus pneumoniae D39	47.644	86.036	0.41
clpP	Streptococcus pneumoniae R6	47.644	86.036	0.41
clpP	Streptococcus pneumoniae TIGR4	47.644	86.036	0.41