Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   MA848_RS06140 Genome accession   NZ_CP092018
Coordinates   1210315..1210980 (-) Length   221 a.a.
NCBI ID   WP_052781683.1    Uniprot ID   -
Organism   Campylobacter jejuni subsp. jejuni strain 15363C     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1205315..1215980
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MA848_RS06125 (MA848_06125) groES 1207170..1207430 (+) 261 WP_002825273.1 co-chaperone GroES -
  MA848_RS06130 (MA848_06130) groL 1207451..1209088 (+) 1638 WP_002859291.1 chaperonin GroEL -
  MA848_RS06135 (MA848_06135) dccS 1209132..1210322 (-) 1191 WP_058000600.1 two-component system sensor histidine kinase DccS -
  MA848_RS06140 (MA848_06140) ciaR 1210315..1210980 (-) 666 WP_052781683.1 two-component system response regulator DccR Regulator
  MA848_RS06145 (MA848_06145) - 1211128..1211727 (+) 600 WP_002898488.1 bacteriohemerythrin -
  MA848_RS06150 (MA848_06150) - 1211738..1211986 (+) 249 WP_058000599.1 ribbon-helix-helix domain-containing protein -
  MA848_RS06160 (MA848_06160) - 1212241..1213488 (-) 1248 WP_002853920.1 ArsS family sensor histidine kinase -
  MA848_RS06165 (MA848_06165) - 1213485..1214159 (-) 675 WP_002853196.1 response regulator transcription factor -
  MA848_RS06170 (MA848_06170) htrA 1214235..1215653 (-) 1419 WP_002869642.1 serine protease HtrA -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25589.31 Da        Isoelectric Point: 4.7578

>NTDB_id=564203 MA848_RS06140 WP_052781683.1 1210315..1210980(-) (ciaR) [Campylobacter jejuni subsp. jejuni strain 15363C]
MAAKILLLEDDLSLSEIIEEFLNDEGYEVFLCDNAQEALDMAYERYFDLWILDVKVPLGDGFSLLKELRKSGKQTPAIFM
TSLNTTNDLKQGFEAGCDDYIKKPFELAELSIRVKALLKRAFSHKNEDFEDLGGGFRFEFTTQILYHNNKALTLPSKEIK
LLSLLLKNKNNFLSTERIFEELWDYDEEPSELSLRAYVKNLRKILGKEKIINQRGRGYCYG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=564203 MA848_RS06140 WP_052781683.1 1210315..1210980(-) (ciaR) [Campylobacter jejuni subsp. jejuni strain 15363C]
ATGGCTGCTAAAATTTTACTTTTAGAAGATGATTTGAGCTTGAGTGAGATCATTGAAGAGTTTTTAAACGATGAGGGATA
TGAAGTATTTTTATGCGATAATGCGCAAGAAGCTTTAGATATGGCTTATGAAAGATATTTTGATCTTTGGATTTTAGATG
TAAAAGTTCCTTTAGGAGATGGATTTTCATTACTTAAAGAATTGAGAAAAAGTGGAAAGCAAACTCCAGCAATTTTCATG
ACTTCTTTAAACACAACAAACGATTTAAAACAAGGCTTTGAAGCAGGTTGTGATGATTATATAAAAAAACCTTTTGAACT
TGCCGAGTTATCTATTAGGGTTAAAGCTTTGCTTAAAAGAGCTTTTTCACATAAAAATGAAGATTTTGAAGATTTAGGGG
GTGGATTTAGATTTGAATTTACTACACAAATTCTTTATCATAATAATAAAGCCTTGACTTTACCGAGTAAAGAAATAAAG
CTTTTGTCTTTATTGCTTAAAAATAAAAACAACTTTTTAAGCACAGAGAGAATTTTTGAAGAACTCTGGGATTATGATGA
GGAGCCTAGTGAGCTAAGTTTAAGGGCTTATGTGAAAAATTTACGTAAAATTTTAGGAAAAGAAAAAATTATAAATCAAA
GAGGCAGGGGATATTGCTATGGCTAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-219)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

36.036

100

0.362
  ciaR Streptococcus pneumoniae D39

36.036

100

0.362
  ciaR Streptococcus pneumoniae R6

36.036

100

0.362
  ciaR Streptococcus pneumoniae TIGR4

36.036

100

0.362