Detailed information NTG0564100

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: KHA74_RS17695
• Genome accession: NZ_CP074348
• Coordinates: 3587493..3588656 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain SW5
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3582493..3593656

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KHA74_RS17665 (KHA74_17585)	-	3582757..3583176 (-)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-
KHA74_RS17670 (KHA74_17590)	comFC	3583250..3583939 (-)	690	WP_217898730.1	phosphoribosyltransferase family protein	Machinery gene
KHA74_RS17675 (KHA74_17595)	-	3583945..3584229 (-)	285	WP_007407481.1	competence protein ComFB	-
KHA74_RS17680 (KHA74_17600)	comFA	3584287..3585672 (-)	1386	WP_094032535.1	DEAD/DEAH box helicase	Machinery gene
KHA74_RS17685 (KHA74_17605)	-	3585781..3586629 (-)	849	WP_003151387.1	DegV family protein	-
KHA74_RS17690 (KHA74_17610)	degU	3586727..3587416 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
KHA74_RS17695 (KHA74_17615)	degS	3587493..3588656 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
KHA74_RS17700 (KHA74_17620)	-	3588879..3589526 (+)	648	WP_061581228.1	YigZ family protein	-
KHA74_RS17705 (KHA74_17625)	-	3589531..3590766 (+)	1236	WP_025285355.1	LCP family protein	-
KHA74_RS17710 (KHA74_17630)	-	3590865..3591941 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
KHA74_RS17715 (KHA74_17635)	-	3592074..3593270 (-)	1197	WP_094032536.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=564100 KHA74_RS17695 WP_007407484.1 3587493..3588656(-) (degS) [Bacillus velezensis strain SW5]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=564100 KHA74_RS17695 WP_007407484.1 3587493..3588656(-) (degS) [Bacillus velezensis strain SW5]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951