Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   MAK06_RS02520 Genome accession   NZ_CP091876
Coordinates   530053..530622 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   A0A0H2XHV7
Organism   Staphylococcus aureus strain FRI-1169     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 525053..535622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MAK06_RS02495 (MAK06_11365) cysE 526266..526913 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  MAK06_RS02500 (MAK06_11360) cysS 526897..528297 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  MAK06_RS02505 (MAK06_11355) - 528290..528694 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  MAK06_RS02510 (MAK06_11350) rlmB 528702..529448 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  MAK06_RS02515 (MAK06_11345) - 529448..529972 (+) 525 WP_000664738.1 NYN domain-containing protein -
  MAK06_RS02520 (MAK06_11340) sigH 530053..530622 (+) 570 WP_000872873.1 RNA polymerase sigma factor Regulator
  MAK06_RS02525 (MAK06_11335) rpmG 530737..530880 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  MAK06_RS02530 (MAK06_11330) secE 530936..531118 (+) 183 WP_001074474.1 preprotein translocase subunit SecE -
  MAK06_RS02535 (MAK06_11325) nusG 531131..531679 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  MAK06_RS02540 (MAK06_11320) rplK 531860..532282 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  MAK06_RS02545 (MAK06_11315) rplA 532490..533182 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  MAK06_RS02550 (MAK06_11310) rplJ 533454..533954 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  MAK06_RS02555 (MAK06_11305) rplL 533997..534365 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  MAK06_RS02560 (MAK06_11300) - 534540..535148 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=563867 MAK06_RS02520 WP_000872873.1 530053..530622(+) (sigH) [Staphylococcus aureus strain FRI-1169]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=563867 MAK06_RS02520 WP_000872873.1 530053..530622(+) (sigH) [Staphylococcus aureus strain FRI-1169]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterProScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XHV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984