Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L7H22_RS05150 Genome accession   NZ_CP091839
Coordinates   1051844..1052500 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain SWYHX138.261ft     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1046844..1057500
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L7H22_RS05120 (L7H22_05120) yecA 1048095..1048760 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  L7H22_RS05140 (L7H22_05140) pgsA 1049410..1049958 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  L7H22_RS05145 (L7H22_05145) uvrC 1050015..1051847 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  L7H22_RS05150 (L7H22_05150) letA 1051844..1052500 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  L7H22_RS22720 - 1052642..1052758 (+) 117 WP_001302039.1 hypothetical protein -
  L7H22_RS05155 (L7H22_05155) yecU 1052796..1052972 (+) 177 WP_238059163.1 protein YecU -
  L7H22_RS05160 (L7H22_05160) yecF 1052959..1053183 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  L7H22_RS05165 (L7H22_05165) sdiA 1053251..1053973 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  L7H22_RS05170 (L7H22_05170) tcyN 1054203..1054955 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  L7H22_RS05175 (L7H22_05175) tcyL 1054952..1055620 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  L7H22_RS05180 (L7H22_05180) dcyD 1055635..1056621 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=563697 L7H22_RS05150 WP_000611335.1 1051844..1052500(-) (letA) [Escherichia coli strain SWYHX138.261ft]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=563697 L7H22_RS05150 WP_000611335.1 1051844..1052500(-) (letA) [Escherichia coli strain SWYHX138.261ft]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACTGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486