Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L6V99_RS09670 Genome accession   NZ_CP091773
Coordinates   1988834..1989490 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain SWYH.B349aT     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1983834..1994490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6V99_RS09640 (L6V99_09640) dcyD 1984714..1985700 (+) 987 WP_001128213.1 D-cysteine desulfhydrase -
  L6V99_RS09645 (L6V99_09645) tcyL 1985715..1986383 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  L6V99_RS09650 (L6V99_09650) tcyN 1986380..1987132 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  L6V99_RS09655 (L6V99_09655) sdiA 1987362..1988084 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  L6V99_RS09660 (L6V99_09660) yecF 1988151..1988375 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  L6V99_RS09665 (L6V99_09665) yecU 1988362..1988538 (-) 177 WP_001307856.1 protein YecU -
  L6V99_RS24230 - 1988621..1988692 (-) 72 Protein_1899 transcriptional regulator -
  L6V99_RS09670 (L6V99_09670) letA 1988834..1989490 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  L6V99_RS09675 (L6V99_09675) uvrC 1989487..1991319 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  L6V99_RS09680 (L6V99_09680) pgsA 1991376..1991924 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  L6V99_RS09700 (L6V99_09700) yecA 1992574..1993239 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=563497 L6V99_RS09670 WP_000611328.1 1988834..1989490(+) (letA) [Escherichia coli strain SWYH.B349aT]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=563497 L6V99_RS09670 WP_000611328.1 1988834..1989490(+) (letA) [Escherichia coli strain SWYH.B349aT]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482