Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L6507_RS09935 Genome accession   NZ_CP091756
Coordinates   2074952..2075608 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain LC-1302-2020     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2069952..2080608
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6507_RS09905 (L6507_09905) dcyD 2070832..2071818 (+) 987 WP_001128222.1 D-cysteine desulfhydrase -
  L6507_RS09910 (L6507_09910) tcyL 2071833..2072501 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  L6507_RS09915 (L6507_09915) tcyN 2072498..2073250 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  L6507_RS09920 (L6507_09920) sdiA 2073480..2074202 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  L6507_RS09925 (L6507_09925) yecF 2074269..2074493 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  L6507_RS09930 (L6507_09930) yecU 2074480..2074656 (-) 177 WP_001326718.1 protein YecU -
  L6507_RS26430 - 2074739..2074810 (-) 72 Protein_1950 transcriptional regulator -
  L6507_RS09935 (L6507_09935) letA 2074952..2075608 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  L6507_RS09940 (L6507_09940) uvrC 2075605..2077437 (+) 1833 WP_001283429.1 excinuclease ABC subunit UvrC Machinery gene
  L6507_RS09945 (L6507_09945) pgsA 2077494..2078042 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  L6507_RS09965 (L6507_09965) yecA 2078692..2079357 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=563373 L6507_RS09935 WP_000611335.1 2074952..2075608(+) (letA) [Escherichia coli strain LC-1302-2020]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=563373 L6507_RS09935 WP_000611335.1 2074952..2075608(+) (letA) [Escherichia coli strain LC-1302-2020]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486