Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L6L54_RS13265 Genome accession   NZ_CP091682
Coordinates   2674644..2675300 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain KKo003     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2669644..2680300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6L54_RS13235 (L6L54_13235) yecA 2670896..2671561 (-) 666 WP_000847877.1 UPF0149 family protein YecA -
  L6L54_RS13255 (L6L54_13255) pgsA 2672210..2672758 (-) 549 WP_001538881.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  L6L54_RS13260 (L6L54_13260) uvrC 2672815..2674647 (-) 1833 WP_001773939.1 excinuclease ABC subunit UvrC Machinery gene
  L6L54_RS13265 (L6L54_13265) letA 2674644..2675300 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  L6L54_RS13270 (L6L54_13270) yecU 2675596..2675772 (+) 177 WP_001307856.1 protein YecU -
  L6L54_RS13275 (L6L54_13275) yecF 2675759..2675983 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  L6L54_RS13280 (L6L54_13280) sdiA 2676051..2676773 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  L6L54_RS13285 (L6L54_13285) tcyN 2677003..2677755 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  L6L54_RS13290 (L6L54_13290) tcyL 2677752..2678420 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  L6L54_RS13295 (L6L54_13295) dcyD 2678435..2679421 (-) 987 WP_001128237.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=562869 L6L54_RS13265 WP_000611328.1 2674644..2675300(-) (letA) [Escherichia coli strain KKo003]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=562869 L6L54_RS13265 WP_000611328.1 2674644..2675300(-) (letA) [Escherichia coli strain KKo003]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTTAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482