Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L6L68_RS13435 Genome accession   NZ_CP091673
Coordinates   2529906..2530562 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain KKo009     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2524906..2535562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6L68_RS13405 (L6L68_13405) yecA 2526157..2526822 (-) 666 WP_000847885.1 UPF0149 family protein YecA -
  L6L68_RS13425 (L6L68_13425) pgsA 2527472..2528020 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  L6L68_RS13430 (L6L68_13430) uvrC 2528077..2529909 (-) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  L6L68_RS13435 (L6L68_13435) letA 2529906..2530562 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  L6L68_RS25375 - 2530704..2530820 (+) 117 WP_001302039.1 hypothetical protein -
  L6L68_RS13440 (L6L68_13440) yecU 2530858..2531034 (+) 177 WP_000590344.1 protein YecU -
  L6L68_RS13445 (L6L68_13445) yecF 2531021..2531245 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  L6L68_RS13450 (L6L68_13450) sdiA 2531312..2532034 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  L6L68_RS13455 (L6L68_13455) tcyN 2532264..2533016 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  L6L68_RS13460 (L6L68_13460) tcyL 2533013..2533681 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  L6L68_RS13465 (L6L68_13465) dcyD 2533696..2534682 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=562702 L6L68_RS13435 WP_000611335.1 2529906..2530562(-) (letA) [Escherichia coli strain KKo009]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=562702 L6L68_RS13435 WP_000611335.1 2529906..2530562(-) (letA) [Escherichia coli strain KKo009]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486