Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L6L61_RS20035 Genome accession   NZ_CP091659
Coordinates   3968796..3969452 (+) Length   218 a.a.
NCBI ID   WP_169772894.1    Uniprot ID   -
Organism   Escherichia coli strain KFu024     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3963796..3974452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6L61_RS19995 (L6L61_19970) dcyD 3963898..3964884 (+) 987 WP_001565616.1 D-cysteine desulfhydrase -
  L6L61_RS20000 (L6L61_19975) tcyL 3964899..3965567 (+) 669 WP_001456221.1 cystine ABC transporter permease -
  L6L61_RS20005 (L6L61_19980) tcyN 3965564..3966316 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  L6L61_RS20010 (L6L61_19985) sdiA 3966546..3967196 (+) 651 Protein_3737 transcriptional regulator SdiA -
  L6L61_RS20020 (L6L61_19995) - 3967935..3968045 (+) 111 Protein_3739 transcriptional regulator SdiA -
  L6L61_RS20025 (L6L61_20000) yecF 3968113..3968337 (-) 225 WP_000106473.1 DUF2594 family protein YecF -
  L6L61_RS20030 (L6L61_20005) yecU 3968324..3968500 (-) 177 WP_000590344.1 protein YecU -
  L6L61_RS25150 - 3968538..3968654 (-) 117 WP_001302039.1 hypothetical protein -
  L6L61_RS20035 (L6L61_20010) letA 3968796..3969452 (+) 657 WP_169772894.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  L6L61_RS20040 (L6L61_20015) uvrC 3969449..3971281 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  L6L61_RS20045 (L6L61_20020) pgsA 3971338..3971886 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  L6L61_RS20065 (L6L61_20040) yecA 3972536..3973201 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23889.65 Da        Isoelectric Point: 6.9614

>NTDB_id=562413 L6L61_RS20035 WP_169772894.1 3968796..3969452(+) (letA) [Escherichia coli strain KFu024]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMNMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=562413 L6L61_RS20035 WP_169772894.1 3968796..3969452(+) (letA) [Escherichia coli strain KFu024]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAATATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482