Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L6L63_RS03265 Genome accession   NZ_CP091652
Coordinates   640373..641029 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain KMi025     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 635373..646029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6L63_RS03255 (L6L63_03255) pgsA 637939..638487 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  L6L63_RS03260 (L6L63_03260) uvrC 638544..640376 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  L6L63_RS03265 (L6L63_03265) letA 640373..641029 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  L6L63_RS25345 - 641171..641242 (+) 72 Protein_642 transcriptional regulator -
  L6L63_RS03270 (L6L63_03270) yecU 641325..641501 (+) 177 WP_001326718.1 protein YecU -
  L6L63_RS03275 (L6L63_03275) yecF 641488..641712 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  L6L63_RS03280 (L6L63_03280) sdiA 641779..642501 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  L6L63_RS03285 (L6L63_03285) tcyN 642731..643483 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  L6L63_RS03290 (L6L63_03290) tcyL 643480..644148 (-) 669 WP_001158218.1 cystine ABC transporter permease -
  L6L63_RS03295 (L6L63_03295) dcyD 644163..645149 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=562270 L6L63_RS03265 WP_000611335.1 640373..641029(-) (letA) [Escherichia coli strain KMi025]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=562270 L6L63_RS03265 WP_000611335.1 640373..641029(-) (letA) [Escherichia coli strain KMi025]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486