Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L6D13_RS09860 Genome accession   NZ_CP091534
Coordinates   2066241..2066897 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 537-20     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2061241..2071897
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6D13_RS09830 (L6D13_09830) dcyD 2062120..2063106 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  L6D13_RS09835 (L6D13_09835) tcyL 2063121..2063789 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  L6D13_RS09840 (L6D13_09840) tcyN 2063786..2064538 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  L6D13_RS09845 (L6D13_09845) sdiA 2064768..2065490 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  L6D13_RS09850 (L6D13_09850) yecF 2065558..2065782 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  L6D13_RS09855 (L6D13_09855) yecU 2065769..2065945 (-) 177 WP_000590344.1 protein YecU -
  L6D13_RS24870 - 2065983..2066099 (-) 117 Protein_1936 transcriptional regulator -
  L6D13_RS09860 (L6D13_09860) letA 2066241..2066897 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  L6D13_RS09865 (L6D13_09865) uvrC 2066894..2068726 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  L6D13_RS09870 (L6D13_09870) pgsA 2068783..2069331 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  L6D13_RS09890 (L6D13_09890) yecA 2069981..2070646 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=562015 L6D13_RS09860 WP_000611335.1 2066241..2066897(+) (letA) [Escherichia coli strain 537-20]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=562015 L6D13_RS09860 WP_000611335.1 2066241..2066897(+) (letA) [Escherichia coli strain 537-20]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486