Detailed information NTG0561803

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV29_RS05050
• Genome accession: NZ_CP073878
• Coordinates: 946505..947551 (+)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain B1285228
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 941505..952551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV29_RS05025 (KFV29_05025)	-	942646..943182 (+)	537	WP_002470337.1	hypothetical protein	-
KFV29_RS05030 (KFV29_05030)	-	943333..944319 (-)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV29_RS05035 (KFV29_05035)	map	944493..945248 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV29_RS05040 (KFV29_05040)	-	945406..945792 (+)	387	WP_001830382.1	hypothetical protein	-
KFV29_RS05045 (KFV29_05045)	liaF	945807..946508 (+)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV29_RS05050 (KFV29_05050)	vraS	946505..947551 (+)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV29_RS05055 (KFV29_05055)	vraR	947541..948170 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV29_RS05060 (KFV29_05060)	-	948227..949405 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV29_RS05065 (KFV29_05065)	-	949812..950096 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV29_RS05070 (KFV29_05070)	-	950104..950568 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV29_RS05075 (KFV29_05075)	-	950709..950924 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV29_RS05080 (KFV29_05080)	-	950926..952167 (+)	1242	WP_001832467.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=561803 KFV29_RS05050 WP_001830374.1 946505..947551(+) (vraS) [Staphylococcus epidermidis strain B1285228]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=561803 KFV29_RS05050 WP_001830374.1 946505..947551(+) (vraS) [Staphylococcus epidermidis strain B1285228]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92