Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | KFV37_RS00360 | Genome accession | NZ_CP073876 |
| Coordinates | 63974..65335 (-) | Length | 453 a.a. |
| NCBI ID | WP_001631036.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain B1285135 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 62349..111010 | 63974..65335 | within | 0 |
Gene organization within MGE regions
Location: 62349..111010
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFV37_RS00355 (KFV37_00355) | ccrB | 62349..63977 (-) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
| KFV37_RS00360 (KFV37_00360) | ccrA | 63974..65335 (-) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| KFV37_RS00365 (KFV37_00365) | - | 65522..66151 (-) | 630 | Protein_54 | hypothetical protein | - |
| KFV37_RS00370 (KFV37_00370) | - | 66160..66498 (+) | 339 | Protein_55 | recombinase family protein | - |
| KFV37_RS00375 (KFV37_00375) | - | 66610..66969 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| KFV37_RS00380 (KFV37_00380) | - | 67176..67502 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV37_RS00385 (KFV37_00385) | - | 67832..69757 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| KFV37_RS00390 (KFV37_00390) | - | 71009..71314 (+) | 306 | WP_000677987.1 | hypothetical protein | - |
| KFV37_RS00395 (KFV37_00395) | - | 71512..72375 (+) | 864 | WP_000680579.1 | hypothetical protein | - |
| KFV37_RS00400 (KFV37_00400) | - | 72483..73958 (+) | 1476 | WP_001138664.1 | DUF6038 family protein | - |
| KFV37_RS00405 (KFV37_00405) | - | 74185..75285 (+) | 1101 | WP_000449985.1 | DNA polymerase | - |
| KFV37_RS00410 (KFV37_00410) | - | 75278..75649 (+) | 372 | WP_001058157.1 | hypothetical protein | - |
| KFV37_RS00415 (KFV37_00415) | - | 75646..77289 (+) | 1644 | WP_012086574.1 | DUF5906 domain-containing protein | - |
| KFV37_RS00420 (KFV37_00420) | - | 77516..79192 (+) | 1677 | WP_012086571.1 | recombinase family protein | - |
| KFV37_RS00425 (KFV37_00425) | - | 79298..79636 (+) | 339 | WP_012086569.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV37_RS00430 (KFV37_00430) | - | 79732..80043 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| KFV37_RS00435 (KFV37_00435) | - | 80059..80565 (+) | 507 | WP_012086564.1 | DUF1643 domain-containing protein | - |
| KFV37_RS00440 (KFV37_00440) | - | 80593..81039 (+) | 447 | WP_012086562.1 | JAB domain-containing protein | - |
| KFV37_RS00445 (KFV37_00445) | - | 81209..82081 (+) | 873 | WP_012086560.1 | HTH domain-containing protein | - |
| KFV37_RS00450 (KFV37_00450) | - | 82133..82423 (+) | 291 | WP_012086558.1 | hypothetical protein | - |
| KFV37_RS00460 (KFV37_00460) | - | 82646..82801 (+) | 156 | Protein_72 | metal-sensing transcriptional repressor | - |
| KFV37_RS00465 (KFV37_00465) | - | 82798..83556 (+) | 759 | WP_000623679.1 | sulfite exporter TauE/SafE family protein | - |
| KFV37_RS00470 (KFV37_00470) | - | 83726..83935 (+) | 210 | Protein_74 | heavy metal translocating P-type ATPase | - |
| KFV37_RS00475 (KFV37_00475) | - | 83953..84498 (+) | 546 | WP_031869236.1 | YdhK family protein | - |
| KFV37_RS00480 (KFV37_00480) | - | 84941..86197 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| KFV37_RS00485 (KFV37_00485) | - | 86642..87316 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| KFV37_RS00490 (KFV37_00490) | - | 87400..87741 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| KFV37_RS00495 (KFV37_00495) | - | 88538..89281 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| KFV37_RS00500 (KFV37_00500) | - | 89378..89806 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| KFV37_RS00505 (KFV37_00505) | mecA | 89852..91861 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| KFV37_RS00510 (KFV37_00510) | mecR1 | 91958..93715 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KFV37_RS00515 (KFV37_00515) | mecI | 93715..94086 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KFV37_RS00520 (KFV37_00520) | psm-mec | 94171..94239 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KFV37_RS00525 (KFV37_00525) | - | 94573..95703 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| KFV37_RS00530 (KFV37_00530) | cstB | 95817..97151 (-) | 1335 | Protein_86 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KFV37_RS00535 (KFV37_00535) | - | 97184..98248 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KFV37_RS00540 (KFV37_00540) | cstR | 98384..98644 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KFV37_RS00545 (KFV37_00545) | - | 98644..99282 (+) | 639 | Protein_89 | sulfite exporter TauE/SafE family protein | - |
| KFV37_RS00555 (KFV37_00555) | - | 99556..100172 (-) | 617 | Protein_90 | CadD family cadmium resistance transporter | - |
| KFV37_RS00560 (KFV37_00560) | - | 100253..102667 (-) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| KFV37_RS00565 (KFV37_00565) | - | 102660..103025 (-) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV37_RS00570 (KFV37_00570) | - | 103263..103640 (-) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| KFV37_RS00575 (KFV37_00575) | - | 103647..105539 (-) | 1893 | WP_002485298.1 | site-specific integrase | - |
| KFV37_RS00580 (KFV37_00580) | - | 105734..106057 (-) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| KFV37_RS00585 (KFV37_00585) | - | 106050..106256 (-) | 207 | WP_001077283.1 | hypothetical protein | - |
| KFV37_RS00590 (KFV37_00590) | - | 106258..106779 (-) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| KFV37_RS00595 (KFV37_00595) | - | 106798..107109 (-) | 312 | WP_000833212.1 | DUF960 family protein | - |
| KFV37_RS00600 (KFV37_00600) | - | 107194..107544 (-) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV37_RS00605 (KFV37_00605) | ccrB | 108015..109643 (-) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| KFV37_RS00610 (KFV37_00610) | ccrA | 109664..111010 (-) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 53316.45 Da Isoelectric Point: 9.8596
>NTDB_id=561759 KFV37_RS00360 WP_001631036.1 63974..65335(-) (ccrA) [Staphylococcus epidermidis strain B1285135]
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
Nucleotide
Download Length: 1362 bp
>NTDB_id=561759 KFV37_RS00360 WP_001631036.1 63974..65335(-) (ccrA) [Staphylococcus epidermidis strain B1285135]
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
54.628 |
97.792 |
0.534 |
| ccrA | Staphylococcus aureus N315 |
50.564 |
97.792 |
0.494 |