Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   L3474_RS02830 Genome accession   NZ_CP091450
Coordinates   552079..552735 (+) Length   218 a.a.
NCBI ID   WP_000697959.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 3641/15     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 547079..557735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3474_RS02800 (L3474_02770) - 547131..547730 (+) 600 WP_001166181.1 hypothetical protein -
  L3474_RS02805 (L3474_02775) - 547873..548043 (+) 171 Protein_550 group II intron maturase-specific domain-containing protein -
  L3474_RS02810 (L3474_02780) - 548400..549677 (+) 1278 WP_001068285.1 ABC transporter permease -
  L3474_RS02815 (L3474_02785) vex2 549690..550337 (+) 648 WP_000173729.1 ABC transporter ATP-binding subunit Vex2 -
  L3474_RS02820 (L3474_02790) vex3 550389..551768 (+) 1380 WP_000902984.1 ABC transporter permease subunit Vex3 -
  L3474_RS02825 (L3474_02795) pep27 551947..552030 (+) 84 WP_199862660.1 putative autolysis signal peptide Pep27 -
  L3474_RS02830 (L3474_02800) ciaR 552079..552735 (+) 657 WP_000697959.1 response regulator transcription factor VncR Regulator
  L3474_RS02835 (L3474_02805) vncS 552732..554060 (+) 1329 WP_000831371.1 sensor histidine kinase VncS -
  L3474_RS02840 (L3474_02810) - 554201..555082 (+) 882 WP_001019003.1 class II fructose-bisphosphate aldolase -
  L3474_RS02845 (L3474_02815) - 555403..556593 (-) 1191 WP_000843701.1 ferric reductase-like transmembrane domain-containing protein -
  L3474_RS02850 (L3474_02820) - 556888..557547 (-) 660 WP_000443837.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25000.70 Da        Isoelectric Point: 4.3898

>NTDB_id=561386 L3474_RS02830 WP_000697959.1 552079..552735(+) (ciaR) [Streptococcus pneumoniae strain 3641/15]
MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYEVALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAF
QDEEYKMSAFASLADGYLEKPFSLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCIFTVRNVGYKLERK

Nucleotide


Download         Length: 657 bp        

>NTDB_id=561386 L3474_RS02830 WP_000697959.1 552079..552735(+) (ciaR) [Streptococcus pneumoniae strain 3641/15]
ATGAAAATTTTAATTGTAGAAGATGAAGAGATGATCCGTGAGGGGGTCAGTGATTATTTGACGGATTGTGGCTATGAAAC
TATTGAGGCAGCGGACGGTCAGGAAGCTCTGGAGCAATTTTCTAGCTATGAGGTGGCCCTGGTTTTACTGGATATCCAGA
TGCCCAAGCTTAACGGCTTAGAAGTCCTAGCTGAGATTCGTAAAACCAGTCAGGTTCCTGTCTTGATGTTGACAGCTTTT
CAGGATGAGGAATACAAGATGAGTGCCTTTGCCTCTTTGGCAGATGGCTATCTGGAAAAACCTTTCTCCCTCTCCCTCTT
AAAAGTGAGGGTGGACGCGATTTTCAAGCGCTACTACGATACAGGACGAATCTTTTCTTACAAGGATACCAAGGTGGACT
TTGAAAGCTACAGTGCAAGCCTCGCAGGTCAAGAAGTGCCTATCAATGCCAAAGAGTTGGAAATTCTGGACTATCTAGTG
AAAAATGAAGGCCGGGCCTTGACTCGGTCTCAGATTATCGATGCCGTCTGGAAAGCGACAGATGAGGTTCCCTTTGACCG
TGTTATTGATGTTTATATCAAGGAATTGCGGAAAAAGCTAGACTTGGATTGTATCTTCACTGTGCGCAATGTTGGTTATA
AATTGGAGCGAAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(143-215)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

34.956

100

0.362
  micA Streptococcus pneumoniae Cp1015

34.802

100

0.362