Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | KFV27_RS00530 | Genome accession | NZ_CP073830 |
| Coordinates | 109032..110660 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186596.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain B1220165 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 63366..112027 | 109032..110660 | within | 0 |
Gene organization within MGE regions
Location: 63366..112027
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFV27_RS00280 (KFV27_00280) | ccrB | 63366..64994 (-) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
| KFV27_RS00285 (KFV27_00285) | ccrA | 64991..66352 (-) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| KFV27_RS00290 (KFV27_00290) | - | 66539..67168 (-) | 630 | Protein_55 | hypothetical protein | - |
| KFV27_RS00295 (KFV27_00295) | - | 67177..67515 (+) | 339 | Protein_56 | recombinase family protein | - |
| KFV27_RS00300 (KFV27_00300) | - | 67627..67986 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| KFV27_RS00305 (KFV27_00305) | - | 68193..68519 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV27_RS00310 (KFV27_00310) | - | 68849..70774 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| KFV27_RS00315 (KFV27_00315) | - | 72026..72331 (+) | 306 | WP_000677987.1 | hypothetical protein | - |
| KFV27_RS00320 (KFV27_00320) | - | 72529..73392 (+) | 864 | WP_000680579.1 | hypothetical protein | - |
| KFV27_RS00325 (KFV27_00325) | - | 73500..74975 (+) | 1476 | WP_001138664.1 | DUF6038 family protein | - |
| KFV27_RS00330 (KFV27_00330) | - | 75202..76302 (+) | 1101 | WP_000449985.1 | DNA polymerase | - |
| KFV27_RS00335 (KFV27_00335) | - | 76295..76666 (+) | 372 | WP_001058157.1 | hypothetical protein | - |
| KFV27_RS00340 (KFV27_00340) | - | 76663..78306 (+) | 1644 | WP_012086574.1 | DUF5906 domain-containing protein | - |
| KFV27_RS00345 (KFV27_00345) | - | 78533..80209 (+) | 1677 | WP_012086571.1 | recombinase family protein | - |
| KFV27_RS00350 (KFV27_00350) | - | 80315..80653 (+) | 339 | WP_012086569.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV27_RS00355 (KFV27_00355) | - | 80749..81060 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| KFV27_RS00360 (KFV27_00360) | - | 81076..81582 (+) | 507 | WP_012086564.1 | DUF1643 domain-containing protein | - |
| KFV27_RS00365 (KFV27_00365) | - | 81610..82056 (+) | 447 | WP_012086562.1 | JAB domain-containing protein | - |
| KFV27_RS00370 (KFV27_00370) | - | 82226..83098 (+) | 873 | WP_012086560.1 | HTH domain-containing protein | - |
| KFV27_RS00375 (KFV27_00375) | - | 83150..83440 (+) | 291 | WP_012086558.1 | hypothetical protein | - |
| KFV27_RS00385 (KFV27_00385) | - | 83663..83818 (+) | 156 | Protein_73 | metal-sensing transcriptional repressor | - |
| KFV27_RS00390 (KFV27_00390) | - | 83815..84573 (+) | 759 | WP_000623679.1 | sulfite exporter TauE/SafE family protein | - |
| KFV27_RS00395 (KFV27_00395) | - | 84743..84952 (+) | 210 | Protein_75 | heavy metal translocating P-type ATPase | - |
| KFV27_RS00400 (KFV27_00400) | - | 84970..85515 (+) | 546 | WP_031869236.1 | YdhK family protein | - |
| KFV27_RS00405 (KFV27_00405) | - | 85958..87214 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| KFV27_RS00410 (KFV27_00410) | - | 87659..88333 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| KFV27_RS00415 (KFV27_00415) | - | 88417..88758 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| KFV27_RS00420 (KFV27_00420) | - | 89555..90298 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| KFV27_RS00425 (KFV27_00425) | - | 90395..90823 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| KFV27_RS00430 (KFV27_00430) | mecA | 90869..92878 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| KFV27_RS00435 (KFV27_00435) | mecR1 | 92975..94732 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KFV27_RS00440 (KFV27_00440) | mecI | 94732..95103 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KFV27_RS00445 (KFV27_00445) | psm-mec | 95188..95256 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KFV27_RS00450 (KFV27_00450) | - | 95611..96720 (+) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| KFV27_RS00455 (KFV27_00455) | cstB | 96834..98168 (-) | 1335 | Protein_87 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KFV27_RS00460 (KFV27_00460) | - | 98201..99265 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KFV27_RS00465 (KFV27_00465) | cstR | 99401..99661 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KFV27_RS00470 (KFV27_00470) | - | 99661..100299 (+) | 639 | Protein_90 | sulfite exporter TauE/SafE family protein | - |
| KFV27_RS00480 (KFV27_00480) | - | 100573..101189 (-) | 617 | Protein_91 | CadD family cadmium resistance transporter | - |
| KFV27_RS00485 (KFV27_00485) | - | 101270..103684 (-) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| KFV27_RS00490 (KFV27_00490) | - | 103677..104042 (-) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV27_RS00495 (KFV27_00495) | - | 104280..104657 (-) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| KFV27_RS00500 (KFV27_00500) | - | 104664..106556 (-) | 1893 | WP_002485298.1 | site-specific integrase | - |
| KFV27_RS00505 (KFV27_00505) | - | 106751..107074 (-) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| KFV27_RS00510 (KFV27_00510) | - | 107067..107273 (-) | 207 | WP_001077283.1 | hypothetical protein | - |
| KFV27_RS00515 (KFV27_00515) | - | 107275..107796 (-) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| KFV27_RS00520 (KFV27_00520) | - | 107815..108126 (-) | 312 | WP_000833212.1 | DUF960 family protein | - |
| KFV27_RS00525 (KFV27_00525) | - | 108211..108561 (-) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV27_RS00530 (KFV27_00530) | ccrB | 109032..110660 (-) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| KFV27_RS00535 (KFV27_00535) | ccrA | 110681..112027 (-) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62274.15 Da Isoelectric Point: 9.7334
>NTDB_id=561118 KFV27_RS00530 WP_001186596.1 109032..110660(-) (ccrB) [Staphylococcus epidermidis strain B1220165]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI
Nucleotide
Download Length: 1629 bp
>NTDB_id=561118 KFV27_RS00530 WP_001186596.1 109032..110660(-) (ccrB) [Staphylococcus epidermidis strain B1220165]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
86.531 |
100 |
0.865 |