Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   KEM15_RS02375 Genome accession   NZ_CP073632
Coordinates   458488..459177 (+) Length   229 a.a.
NCBI ID   WP_217374725.1    Uniprot ID   -
Organism   Streptococcus parasuis strain NN1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 453488..464177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KEM15_RS02350 (KEM15_02320) - 453818..455161 (+) 1344 WP_216807102.1 DEAD/DEAH box helicase -
  KEM15_RS02355 (KEM15_02325) - 455180..455404 (+) 225 WP_130554666.1 DUF4059 family protein -
  KEM15_RS02360 (KEM15_02330) trxB 455417..456334 (+) 918 WP_217374722.1 thioredoxin-disulfide reductase -
  KEM15_RS02365 (KEM15_02335) - 456344..456883 (+) 540 WP_174845818.1 YceD family protein -
  KEM15_RS02370 (KEM15_02340) gndA 456979..458406 (+) 1428 WP_217374724.1 NADP-dependent phosphogluconate dehydrogenase -
  KEM15_RS02375 (KEM15_02345) covR 458488..459177 (+) 690 WP_217374725.1 winged helix-turn-helix domain-containing protein Regulator
  KEM15_RS02380 (KEM15_02350) - 459257..460387 (+) 1131 WP_130554661.1 AI-2E family transporter -
  KEM15_RS02385 (KEM15_02355) - 460590..461837 (+) 1248 WP_239604569.1 aminoacyltransferase -
  KEM15_RS02390 (KEM15_02360) - 461815..463062 (+) 1248 WP_239604570.1 aminoacyltransferase -
  KEM15_RS02395 (KEM15_02365) nrdR 463136..463627 (+) 492 WP_130554659.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26229.20 Da        Isoelectric Point: 6.0391

>NTDB_id=559503 KEM15_RS02375 WP_217374725.1 458488..459177(+) (covR) [Streptococcus parasuis strain NN1]
MAKKILIAGKERNLSHFVSMELQKKEYIVDYASTGKEALSLAHETDFDLVLMSFQLSDMSSKKLAKELLAIKPATVMIVV
VEPTEVADHGEDILTYAVFYVVKPFVISDLVEQISDIFRGRDFIETNCKQVHLHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDVPGQASYIRTVRGVGYTMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=559503 KEM15_RS02375 WP_217374725.1 458488..459177(+) (covR) [Streptococcus parasuis strain NN1]
ATGGCTAAGAAAATTTTGATTGCTGGGAAAGAGCGTAATCTTTCACATTTTGTTTCCATGGAACTTCAGAAGAAGGAGTA
TATCGTTGATTATGCTTCAACAGGGAAAGAAGCTTTATCACTAGCTCATGAGACAGACTTTGATTTGGTTTTGATGAGTT
TCCAATTATCCGATATGTCCAGCAAGAAGTTGGCTAAGGAGCTTCTTGCAATCAAACCTGCTACGGTGATGATTGTAGTT
GTCGAACCAACAGAAGTGGCTGACCATGGGGAAGATATATTGACGTATGCGGTATTTTACGTTGTGAAGCCATTTGTTAT
TAGTGACTTGGTGGAACAAATTTCCGATATTTTCCGTGGTAGAGATTTTATTGAAACGAATTGTAAACAGGTTCATTTGC
ATGCGGCCTATCGAGATTTAAAAGTTGATTTTCAAAACCGAACGGTCACTCGGGGAGATGAGTTAATCAACTTGACACGG
CGAGAATATGATTTGCTGGCGACGTTGATGAATAGTCCGGAACCAGTTAGCCGAGAACAACTTCTTGAACGGGTCTGGAA
GTATGAAGCGGCCTCTGAAACAAATGTTGTGGATGTCTATATTCGTTATCTTCGTGGAAAATTAGATGTTCCAGGACAGG
CTTCCTATATTCGGACGGTACGTGGTGTTGGCTATACCATGAGAGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.66

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432