Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L1P13_RS10190 Genome accession   NZ_CP091024
Coordinates   2065257..2065913 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain STEC379     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2060257..2070913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1P13_RS10160 dcyD 2061137..2062123 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  L1P13_RS10165 tcyL 2062138..2062806 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  L1P13_RS10170 tcyN 2062803..2063555 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  L1P13_RS10175 sdiA 2063785..2064507 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  L1P13_RS10180 yecF 2064574..2064798 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  L1P13_RS10185 yecU 2064785..2064961 (-) 177 WP_000590347.1 protein YecU -
  L1P13_RS25300 - 2065044..2065115 (-) 72 Protein_2004 transcriptional regulator -
  L1P13_RS10190 letA 2065257..2065913 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  L1P13_RS10195 uvrC 2065910..2067742 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  L1P13_RS10200 pgsA 2067799..2068347 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  L1P13_RS10220 yecA 2068997..2069662 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=557630 L1P13_RS10190 WP_000611335.1 2065257..2065913(+) (letA) [Escherichia coli strain STEC379]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=557630 L1P13_RS10190 WP_000611335.1 2065257..2065913(+) (letA) [Escherichia coli strain STEC379]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486