Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L1O96_RS10485 Genome accession   NZ_CP091016
Coordinates   2131442..2132098 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain STEC306     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2126442..2137098
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1O96_RS10455 dcyD 2127321..2128307 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  L1O96_RS10460 tcyL 2128322..2128990 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  L1O96_RS10465 tcyN 2128987..2129739 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  L1O96_RS10470 sdiA 2129969..2130691 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  L1O96_RS10475 yecF 2130759..2130983 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  L1O96_RS10480 yecU 2130970..2131146 (-) 177 WP_000590347.1 protein YecU -
  L1O96_RS26405 - 2131229..2131300 (-) 72 Protein_2056 transcriptional regulator -
  L1O96_RS10485 letA 2131442..2132098 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  L1O96_RS10490 uvrC 2132095..2133927 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  L1O96_RS10495 pgsA 2133984..2134532 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  L1O96_RS10515 yecA 2135182..2135847 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=557306 L1O96_RS10485 WP_000611335.1 2131442..2132098(+) (letA) [Escherichia coli strain STEC306]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=557306 L1O96_RS10485 WP_000611335.1 2131442..2132098(+) (letA) [Escherichia coli strain STEC306]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486