Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   L1A18_RS01770 Genome accession   NZ_CP090887
Coordinates   342158..342790 (+) Length   210 a.a.
NCBI ID   WP_000698438.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP7536     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 337158..347790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A18_RS01745 (L1A18_01745) mvaD 337435..338388 (+) 954 WP_000373456.1 diphosphomevalonate decarboxylase -
  L1A18_RS01750 (L1A18_01750) - 338375..339382 (+) 1008 WP_000562427.1 phosphomevalonate kinase -
  L1A18_RS01755 (L1A18_01755) fni 339366..340376 (+) 1011 WP_000210616.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  L1A18_RS01760 (L1A18_01760) liaF 340454..341152 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  L1A18_RS01765 (L1A18_01765) - 341149..342144 (+) 996 WP_000743662.1 sensor histidine kinase -
  L1A18_RS01770 (L1A18_01770) vraR 342158..342790 (+) 633 WP_000698438.1 response regulator transcription factor Regulator
  L1A18_RS01775 (L1A18_01775) - 342866..343560 (+) 695 Protein_348 DNA alkylation repair protein -
  L1A18_RS01780 (L1A18_01780) - 344019..344621 (+) 603 Protein_349 serine protease -
  L1A18_RS01785 (L1A18_01785) - 344923..345282 (+) 360 WP_000378120.1 tyrosine-type recombinase/integrase -
  L1A18_RS01790 (L1A18_01790) tig 345476..346759 (+) 1284 WP_000116463.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23583.06 Da        Isoelectric Point: 4.5791

>NTDB_id=556934 L1A18_RS01770 WP_000698438.1 342158..342790(+) (vraR) [Streptococcus pneumoniae strain NP7536]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQATVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=556934 L1A18_RS01770 WP_000698438.1 342158..342790(+) (vraR) [Streptococcus pneumoniae strain NP7536]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGACTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41