Detailed information NTG0556542

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: L1A14_RS09345
• Genome accession: NZ_CP090883
• Coordinates: 1803099..1803998 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904867.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain LE4448
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1798099..1808998

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A14_RS09320 (L1A14_09320)	rsmA	1798429..1799301 (-)	873	WP_001216830.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
L1A14_RS09325 (L1A14_09325)	-	1799432..1799740 (-)	309	WP_000333257.1	hypothetical protein	-
L1A14_RS09330 (L1A14_09330)	-	1799733..1800374 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
L1A14_RS09335 (L1A14_09335)	-	1800376..1802406 (-)	2031	WP_000825263.1	bacteriocin-associated integral membrane family protein	-
L1A14_RS09340 (L1A14_09340)	-	1802483..1802779 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
L1A14_RS09345 (L1A14_09345)	comR	1803099..1803998 (-)	900	WP_000904867.1	helix-turn-helix domain-containing protein	Regulator
L1A14_RS09350 (L1A14_09350)	rnmV	1804070..1804630 (-)	561	WP_000664448.1	ribonuclease M5	-
L1A14_RS09355 (L1A14_09355)	-	1804630..1805403 (-)	774	WP_000575607.1	TatD family hydrolase	-
L1A14_RS09360 (L1A14_09360)	-	1805709..1806386 (-)	678	WP_219338615.1	DUF1542 domain-containing protein	-
L1A14_RS09365 (L1A14_09365)	rpmH	1806625..1806759 (-)	135	WP_000831906.1	50S ribosomal protein L34	-
L1A14_RS09370 (L1A14_09370)	-	1806904..1808118 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
L1A14_RS09375 (L1A14_09375)	-	1808274..1808567 (-)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35191.04 Da
• Isoelectric Point: 5.0703

>NTDB_id=556542 L1A14_RS09345 WP_000904867.1 1803099..1803998(-) (comR) [Streptococcus pneumoniae strain LE4448]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=556542 L1A14_RS09345 WP_000904867.1 1803099..1803998(-) (comR) [Streptococcus pneumoniae strain LE4448]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCTTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (7-59)

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368