Detailed information    

insolico Bioinformatically predicted

Overview

Name   recP/tkt   Type   Machinery gene
Locus tag   SMUNUM_RS01445 Genome accession   NZ_AP014571
Coordinates   279868..281844 (+) Length   658 a.a.
NCBI ID   WP_002263527.1    Uniprot ID   Q8DW01
Organism   Streptococcus mutans LP13     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 274868..286844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS01430 (SMNUM_0244) comB/nlmE 274882..275784 (+) 903 WP_002263524.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  SMUNUM_RS01435 (SMNUM_0245) - 276157..277824 (+) 1668 WP_019805321.1 transcription antiterminator -
  SMUNUM_RS01440 (SMNUM_0246) ulaG 278404..279495 (+) 1092 WP_002263526.1 L-ascorbate 6-phosphate lactonase -
  SMUNUM_RS01445 (SMNUM_0247) recP/tkt 279868..281844 (+) 1977 WP_002263527.1 transketolase Machinery gene
  SMUNUM_RS01450 (SMNUM_0248) - 282404..283372 (+) 969 WP_002263528.1 AraC family transcriptional regulator -
  SMUNUM_RS01455 (SMNUM_0249) - 283507..284019 (+) 513 WP_002266701.1 HXXEE domain-containing protein -
  SMUNUM_RS01460 (SMNUM_0250) - 284095..284547 (+) 453 WP_024781646.1 LytTR family DNA-binding domain-containing protein -
  SMUNUM_RS01465 (SMNUM_0251) - 284547..284930 (+) 384 WP_002263531.1 hypothetical protein -
  SMUNUM_RS01470 (SMNUM_0252) - 284948..285922 (+) 975 WP_168747630.1 2-dehydropantoate 2-reductase N-terminal domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 71075.56 Da        Isoelectric Point: 4.7094

>NTDB_id=55501 SMUNUM_RS01445 WP_002263527.1 279868..281844(+) (recP/tkt) [Streptococcus mutans LP13]
MSDLSVNAIRFLGVDAIEKSKSGHPGVVMGAAPMAYSLYTKHLRVNPSQPNWINRDRFVLSAGHGSMLLYALLHLSGFED
ISIDEIKNFRQWGSKTPGHPEYGHTVGVDVTTGPLGQGISMAVGLAQAERFLAAKYNREGYPIFDHYTYVIAGDGDFMEG
VSGEASSYAAKQNLDKLIVLYDSNDICLDGETNDAFTESVRARYDAYGWHTILVEDGNNIEAIGLAIEEAKAAGKPSLIE
IKTVIGYGAPTKGGTNAVHGAPLGAEEAAATRKALNWGYAPFEVPQEVYDDFKENVADRGEAAYDAWSNLVGEYRQAYPK
EAREVDAIIDGKDPVEIKEADFPVYENGFSQATRNSSQDAINAAADVLPNFLGGSADLAHSNMTYIKADGLQDADHPLNR
NIQFGVREFAMGTVLNGMALHGGLRVYGGTFFVFSDYLKAAVRLSALQGVPVTYVFTHDSIAVGEDGPTHEPIEHLAGLR
ATPNLVVFRPADARETQAAWHYALTSQNTPTALVLTRQNLDVEAGSSFTSVAKGAYVTYETDSDFNTILLASGSEVNLAV
KAAKELEAQGEKVRVVSVPSTELFDEQSAAYKEAILPNSVRRRVAIEMAASQPWYKYVGLDGAVIGIDKFGASAPAAQVI
ENYGFTVDNVVKVVKELK

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=55501 SMUNUM_RS01445 WP_002263527.1 279868..281844(+) (recP/tkt) [Streptococcus mutans LP13]
ATGTCAGATTTATCGGTTAATGCCATTCGCTTTTTAGGGGTAGATGCTATTGAAAAGTCTAAGTCGGGTCACCCGGGTGT
TGTCATGGGCGCTGCCCCAATGGCTTACAGTCTATATACTAAGCATTTACGTGTTAACCCAAGTCAGCCAAATTGGATTA
ACCGTGACCGTTTTGTTTTGTCAGCTGGTCATGGCTCAATGCTTTTATATGCTCTCTTGCACTTGTCGGGATTTGAAGAT
ATTTCTATTGATGAAATCAAAAATTTCCGTCAGTGGGGCTCTAAAACACCGGGGCACCCTGAGTATGGCCATACCGTAGG
TGTTGATGTGACAACAGGCCCTCTTGGCCAAGGGATTTCAATGGCTGTTGGTTTGGCTCAAGCTGAACGTTTCTTAGCTG
CTAAATACAATCGTGAAGGCTACCCTATTTTTGATCACTATACTTATGTTATTGCCGGTGATGGTGATTTTATGGAAGGT
GTTTCTGGCGAAGCGTCATCCTATGCTGCCAAACAAAATTTGGATAAACTGATTGTTCTTTATGATTCTAATGATATTTG
TTTGGATGGTGAAACCAATGATGCGTTCACTGAAAGTGTTCGTGCACGATATGATGCTTATGGATGGCATACAATCTTAG
TTGAAGATGGCAATAATATTGAAGCTATTGGACTTGCTATTGAAGAAGCAAAGGCAGCTGGCAAACCTTCTCTTATTGAA
ATTAAAACTGTGATTGGCTACGGTGCTCCAACTAAAGGCGGTACCAATGCTGTTCATGGTGCACCACTTGGAGCTGAAGA
AGCAGCTGCTACTCGTAAGGCTCTCAATTGGGGTTATGCTCCTTTTGAAGTTCCTCAAGAGGTTTATGATGATTTCAAAG
AAAATGTTGCGGATCGTGGTGAAGCTGCTTACGATGCTTGGTCAAATCTTGTTGGAGAATATCGACAAGCTTATCCTAAA
GAGGCGCGTGAAGTGGATGCAATTATTGATGGAAAAGATCCTGTGGAAATCAAAGAAGCTGATTTTCCAGTCTACGAAAA
TGGTTTCTCTCAAGCAACGCGTAATTCTAGTCAAGATGCCATCAATGCTGCGGCAGACGTACTACCTAACTTTCTTGGAG
GATCTGCTGATCTTGCGCATTCTAACATGACTTACATTAAAGCAGATGGGCTTCAAGATGCTGATCATCCGCTTAACCGT
AACATCCAGTTTGGTGTTCGTGAATTTGCTATGGGTACTGTCTTAAATGGTATGGCTCTTCATGGCGGACTGCGTGTTTA
TGGCGGTACCTTCTTTGTCTTTTCAGACTATCTCAAAGCAGCTGTTCGTTTGTCAGCCCTTCAAGGAGTACCAGTAACTT
ATGTCTTTACCCACGATTCGATTGCCGTTGGTGAAGATGGCCCTACTCATGAACCGATTGAACACTTGGCAGGTTTACGT
GCCACTCCTAATTTGGTTGTTTTTCGCCCAGCTGATGCACGCGAAACACAGGCAGCATGGCATTATGCTTTGACAAGCCA
AAACACACCAACAGCTCTTGTTTTGACACGTCAAAATCTTGATGTTGAAGCTGGTTCAAGCTTTACTTCAGTTGCTAAGG
GAGCTTATGTTACTTATGAAACAGATTCTGACTTTAATACCATTCTTTTGGCATCAGGTTCTGAAGTTAACTTAGCAGTC
AAAGCAGCTAAGGAATTGGAAGCACAAGGCGAAAAAGTACGTGTTGTTTCTGTTCCTTCTACAGAGCTCTTTGATGAGCA
ATCTGCTGCCTACAAAGAAGCTATTTTACCAAATTCAGTACGCCGTCGTGTAGCCATTGAAATGGCAGCCAGCCAACCAT
GGTATAAATATGTTGGTCTTGATGGTGCGGTTATCGGTATTGATAAATTTGGAGCATCAGCTCCTGCTGCTCAAGTCATT
GAAAATTATGGCTTTACAGTAGATAATGTGGTTAAAGTTGTTAAGGAACTGAAATAG

Domains

Predicted by InterProScan.

Transketolase, thiamine diphosphate binding domain (Transketolase_N)

(4-334)

Transketolase, pyrimidine binding domain (Transket_pyr)

(352-521)

Transketolase, C-terminal domain (Transketolase_C)

(546-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DW01

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recP/tkt Streptococcus pneumoniae TIGR4

79.3

99.848

0.792

Multiple sequence alignment