Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LZ175_RS09290 Genome accession   NZ_CP090448
Coordinates   1926471..1927127 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain PT62     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1921471..1932127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LZ175_RS09260 (LZ175_09260) dcyD 1922350..1923336 (+) 987 WP_001128238.1 D-cysteine desulfhydrase -
  LZ175_RS09265 (LZ175_09265) tcyL 1923351..1924019 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  LZ175_RS09270 (LZ175_09270) tcyN 1924016..1924768 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LZ175_RS09275 (LZ175_09275) sdiA 1924998..1925720 (+) 723 WP_024231281.1 transcriptional regulator SdiA -
  LZ175_RS09280 (LZ175_09280) yecF 1925788..1926012 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  LZ175_RS09285 (LZ175_09285) yecU 1925999..1926175 (-) 177 WP_001307856.1 protein YecU -
  LZ175_RS09290 (LZ175_09290) letA 1926471..1927127 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LZ175_RS09295 (LZ175_09295) uvrC 1927124..1928956 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  LZ175_RS09300 (LZ175_09300) pgsA 1929013..1929561 (+) 549 WP_001160191.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LZ175_RS09320 (LZ175_09320) yecA 1930210..1930875 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=554059 LZ175_RS09290 WP_000611328.1 1926471..1927127(+) (letA) [Escherichia coli strain PT62]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=554059 LZ175_RS09290 WP_000611328.1 1926471..1927127(+) (letA) [Escherichia coli strain PT62]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482