Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LXF06_RS13700 Genome accession   NZ_CP090305
Coordinates   2863382..2864038 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z503     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2858382..2869038
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXF06_RS13670 dcyD 2859261..2860247 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  LXF06_RS13675 tcyL 2860262..2860930 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  LXF06_RS13680 tcyN 2860927..2861679 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LXF06_RS13685 sdiA 2861909..2862631 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  LXF06_RS13690 yecF 2862699..2862923 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  LXF06_RS13695 yecU 2862910..2863086 (-) 177 WP_000590347.1 protein YecU -
  LXF06_RS22825 - 2863169..2863240 (-) 72 Protein_2673 transcriptional regulator -
  LXF06_RS13700 letA 2863382..2864038 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LXF06_RS13705 uvrC 2864035..2865867 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  LXF06_RS13710 pgsA 2865924..2866472 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LXF06_RS13730 yecA 2867122..2867787 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=553529 LXF06_RS13700 WP_000611335.1 2863382..2864038(+) (letA) [Escherichia coli strain Z503]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=553529 LXF06_RS13700 WP_000611335.1 2863382..2864038(+) (letA) [Escherichia coli strain Z503]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486