Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LXA46_RS01825 Genome accession   NZ_CP089948
Coordinates   367159..367791 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae TIGR4     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 362159..372791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA46_RS01800 (LXA46_01795) mvaD 362437..363390 (+) 954 WP_000373455.1 diphosphomevalonate decarboxylase -
  LXA46_RS01805 (LXA46_01800) - 363377..364384 (+) 1008 WP_000562415.1 phosphomevalonate kinase -
  LXA46_RS01810 (LXA46_01805) fni 364368..365378 (+) 1011 WP_000210618.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  LXA46_RS01815 (LXA46_01810) liaF 365455..366153 (+) 699 WP_001224636.1 cell wall-active antibiotics response protein LiaF -
  LXA46_RS01820 (LXA46_01815) - 366150..367145 (+) 996 WP_000743672.1 sensor histidine kinase -
  LXA46_RS01825 (LXA46_01820) vraR 367159..367791 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  LXA46_RS01830 (LXA46_01825) - 367867..368560 (+) 694 Protein_364 DNA alkylation repair protein -
  LXA46_RS01835 (LXA46_01830) - 368710..368949 (+) 240 WP_000754501.1 hypothetical protein -
  LXA46_RS01840 (LXA46_01835) cbpG 369030..369851 (+) 822 WP_001100143.1 choline-binding protein CbpG -
  LXA46_RS01845 (LXA46_01840) cbpF 369870..370892 (+) 1023 WP_000771060.1 choline-binding protein CbpF -
  LXA46_RS01850 (LXA46_01845) - 371020..372360 (-) 1341 Protein_368 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=552648 LXA46_RS01825 WP_000698434.1 367159..367791(+) (vraR) [Streptococcus pneumoniae TIGR4]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=552648 LXA46_RS01825 WP_000698434.1 367159..367791(+) (vraR) [Streptococcus pneumoniae TIGR4]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41