Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LVO07_RS17695 Genome accession   NZ_CP089930
Coordinates   3755917..3756573 (+) Length   218 a.a.
NCBI ID   WP_000611331.1    Uniprot ID   A0A370V8A6
Organism   Escherichia coli strain E69     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3750917..3761573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LVO07_RS17660 (LVO07_17660) - 3751424..3751555 (-) 132 Protein_3441 integrase -
  LVO07_RS17665 (LVO07_17665) dcyD 3751795..3752781 (+) 987 WP_225762543.1 D-cysteine desulfhydrase -
  LVO07_RS17670 (LVO07_17670) tcyL 3752796..3753464 (+) 669 WP_032225570.1 cystine ABC transporter permease -
  LVO07_RS17675 (LVO07_17675) tcyN 3753461..3754213 (+) 753 WP_137325895.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LVO07_RS17680 (LVO07_17680) sdiA 3754444..3755166 (+) 723 WP_233073939.1 transcriptional regulator SdiA -
  LVO07_RS17685 (LVO07_17685) yecF 3755233..3755457 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  LVO07_RS17690 (LVO07_17690) - 3755444..3755620 (-) 177 WP_032155896.1 hypothetical protein -
  LVO07_RS17695 (LVO07_17695) letA 3755917..3756573 (+) 657 WP_000611331.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LVO07_RS17700 (LVO07_17700) uvrC 3756570..3758402 (+) 1833 WP_000116018.1 excinuclease ABC subunit UvrC Machinery gene
  LVO07_RS17705 (LVO07_17705) pgsA 3758459..3759007 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LVO07_RS17725 (LVO07_17725) yecA 3759655..3760320 (+) 666 WP_000847898.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23906.68 Da        Isoelectric Point: 6.9614

>NTDB_id=552622 LVO07_RS17695 WP_000611331.1 3755917..3756573(+) (letA) [Escherichia coli strain E69]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANTVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLTSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=552622 LVO07_RS17695 WP_000611331.1 3755917..3756573(+) (letA) [Escherichia coli strain E69]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
TAAAGTCGTCGGTGAGGCATCCTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAACACCGTTGACGTCGTGCTAATGG
ACATGAGTATGCCTGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCTCGCTCGACAGCAGATGTCAAAATCATCATG
CTTACGGTTCATACTGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTATCTCAGCAAAGGTGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGCTCTGTCTATTCGGGGCAGCGTTATATTGCTTCTGACATTGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATTACCAAAGGCCAAAAGGTCAATGAGATCTCAGAACAGCTTAATCTCAGCCCGAAAACGGTGAACAGCTATCGCTACCG
TATGTTCAGTAAATTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTAACAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A370V8A6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

49.083

100

0.491
  letA Legionella pneumophila strain ERS1305867

49.083

100

0.491