Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   LRS74_RS14445 Genome accession   NZ_CP089746
Coordinates   3376931..3377989 (+) Length   352 a.a.
NCBI ID   WP_186318964.1    Uniprot ID   -
Organism   Streptomyces sp. LX-29     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3371931..3382989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LRS74_RS14435 (LRS74_14420) - 3372760..3375030 (-) 2271 WP_277741378.1 sigma-70 family RNA polymerase sigma factor -
  LRS74_RS14440 (LRS74_14425) radA/sms 3375261..3376658 (+) 1398 WP_277741379.1 DNA repair protein RadA Machinery gene
  LRS74_RS14445 (LRS74_14430) disA 3376931..3377989 (+) 1059 WP_186318964.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  LRS74_RS14450 (LRS74_14435) - 3378291..3379145 (-) 855 WP_277741380.1 hypothetical protein -
  LRS74_RS14455 (LRS74_14440) - 3379321..3379977 (+) 657 WP_277741381.1 phosphatase PAP2 family protein -
  LRS74_RS14460 (LRS74_14445) - 3380112..3380804 (-) 693 WP_277741382.1 response regulator transcription factor -
  LRS74_RS14465 (LRS74_14450) - 3380825..3382780 (-) 1956 WP_277741383.1 histidine kinase -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 38226.97 Da        Isoelectric Point: 5.0028

>NTDB_id=552416 LRS74_RS14445 WP_186318964.1 3376931..3377989(+) (disA) [Streptomyces sp. LX-29]
MRASLSAVAPGTALRDGLERVLRGNTGGLIVLGMDKTVESICSGGFVLDVEFSATRLRELCKLDGAMILDKDITKIVRAG
VQLVPDASIPTEETGTRHRTAQRVSIQSGFPVVSVSQSMRLIALYVDGERRVLEESAAILSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIAGVEPERELVVRDYVPEPTAKRT
RTVPEALAELDRLSHAELLEMPIVARALGYSGSPETLDGAVSPRGYRLLAKVPRLPGAIIERLVEHFGGLQKLLAASVDD
LQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=552416 LRS74_RS14445 WP_186318964.1 3376931..3377989(+) (disA) [Streptomyces sp. LX-29]
ATGCGCGCCTCGCTGAGCGCCGTCGCGCCCGGCACGGCGCTGCGCGACGGTCTGGAGCGCGTCCTGCGGGGCAACACGGG
CGGCCTCATCGTGCTCGGCATGGACAAGACCGTCGAGTCCATCTGTAGCGGCGGCTTCGTGCTGGACGTCGAGTTCTCCG
CGACGCGGCTGCGCGAGCTGTGCAAGCTGGACGGCGCGATGATCCTGGACAAGGACATCACCAAGATCGTGCGGGCGGGG
GTCCAGCTGGTCCCGGACGCGTCGATTCCGACCGAGGAGACCGGCACCCGGCACCGCACCGCGCAGCGCGTCTCCATCCA
GAGCGGCTTCCCGGTGGTCTCGGTCAGCCAGTCGATGCGGCTGATCGCGCTCTACGTGGACGGGGAGCGGCGGGTCCTGG
AGGAGTCGGCCGCGATCCTCTCCCGCGCCAACCAGGCGCTGGCCACCCTGGAGCGCTACAAGCTCCGGCTGGACGAGGTC
GCCGGCACCCTCTCCGCCCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTCTCGGCGGTCGCGCAGCGCCTGGAGAT
GGTGCGCCGCATCGCCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACCGACGGCCGGCTGCTCTCCCTCCAGCTCG
ACGAGTTGATCGCGGGCGTGGAGCCGGAGCGGGAGCTGGTGGTCCGCGACTACGTTCCGGAGCCGACCGCCAAGCGCACC
CGCACGGTGCCCGAGGCCCTCGCCGAGCTGGACCGGCTCAGCCACGCCGAGCTGCTCGAAATGCCCATCGTGGCGCGGGC
GCTGGGCTACAGCGGCTCGCCCGAAACGCTCGACGGGGCGGTCTCGCCGCGTGGTTACCGCCTGCTGGCCAAGGTGCCGC
GGCTCCCCGGCGCCATCATCGAGCGGCTCGTCGAGCACTTCGGCGGGCTCCAGAAGCTGCTCGCCGCCAGCGTGGACGAC
CTGCAGACGGTCGACGGCGTGGGCGAGGCGCGGGCCCGTTCGGTGCGCGAGGGCCTCTCCCGGCTGGCCGAGTCCTCGAT
CCTGGAGCGGTACGTGTAA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(133-275)

Helix-hairpin-helix motif (HHH_2)

(302-337)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(16-129)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

47.399

98.295

0.466