Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   LUU82_RS04725 Genome accession   NZ_CP089586
Coordinates   927301..929082 (-) Length   593 a.a.
NCBI ID   WP_000390531.1    Uniprot ID   -
Organism   Staphylococcus aureus strain E1185_IV_ST12     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 922301..934082
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUU82_RS04705 (LUU82_04705) racE 922694..923494 (-) 801 WP_001039659.1 glutamate racemase -
  LUU82_RS04710 (LUU82_04710) sdhB 923730..924545 (-) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  LUU82_RS04715 (LUU82_04715) sdhA 924545..926311 (-) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  LUU82_RS04720 (LUU82_04720) - 926363..926977 (-) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  LUU82_RS04725 (LUU82_04725) uvrC 927301..929082 (-) 1782 WP_000390531.1 excinuclease ABC subunit UvrC Machinery gene
  LUU82_RS04730 (LUU82_04730) - 929248..929343 (+) 96 WP_001788625.1 hypothetical protein -
  LUU82_RS04735 (LUU82_04735) trxA 929406..929720 (-) 315 WP_001018928.1 thioredoxin -
  LUU82_RS04740 (LUU82_04740) mutS/mutS2 929893..932241 (-) 2349 WP_001249299.1 endonuclease MutS2 Machinery gene
  LUU82_RS04745 (LUU82_04745) polX 932251..933963 (-) 1713 WP_000161934.1 DNA polymerase/3'-5' exonuclease PolX -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68670.37 Da        Isoelectric Point: 9.8215

>NTDB_id=552083 LUU82_RS04725 WP_000390531.1 927301..929082(-) (uvrC) [Staphylococcus aureus strain E1185_IV_ST12]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNNKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=552083 LUU82_RS04725 WP_000390531.1 927301..929082(-) (uvrC) [Staphylococcus aureus strain E1185_IV_ST12]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGAGATCATATTTTACGGGTGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGTTTTGAGTTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATAAAACAATATCAACCAAGATATAATATATTATTAAAGGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAGAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTGACAAACAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCAAGAACGATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGACGGTAAACCAGATAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATAATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAGGCATTTTATTTGTTGCATCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAACAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae R6

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae D39

57.265

98.651

0.565