Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   LUV23_RS25645 Genome accession   NZ_CP089536
Coordinates   6284677..6285735 (-) Length   352 a.a.
NCBI ID   WP_069873662.1    Uniprot ID   A0A9X2M0H5
Organism   Streptomyces sp. HNM0561     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 6279677..6290735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUV23_RS25625 (LUV23_25625) - 6279878..6280606 (-) 729 WP_232564640.1 LppP/LprE family lipoprotein -
  LUV23_RS25630 (LUV23_25630) - 6280594..6281205 (-) 612 WP_069873518.1 SigE family RNA polymerase sigma factor -
  LUV23_RS25635 (LUV23_25635) - 6281596..6282522 (-) 927 WP_069873517.1 A/G-specific adenine glycosylase -
  LUV23_RS25640 (LUV23_25640) - 6282815..6283693 (+) 879 WP_206333002.1 hypothetical protein -
  LUV23_RS25645 (LUV23_25645) disA 6284677..6285735 (-) 1059 WP_069873662.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  LUV23_RS25650 (LUV23_25650) radA/sms 6286262..6287686 (-) 1425 WP_069873511.1 DNA repair protein RadA Machinery gene
  LUV23_RS25655 (LUV23_25655) - 6287887..6289596 (+) 1710 WP_069873509.1 sigma-70 family RNA polymerase sigma factor -
  LUV23_RS25660 (LUV23_25660) - 6289721..6290647 (-) 927 WP_206333003.1 hypothetical protein -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 38219.98 Da        Isoelectric Point: 5.0869

>NTDB_id=551995 LUV23_RS25645 WP_069873662.1 6284677..6285735(-) (disA) [Streptomyces sp. HNM0561]
MRASLSAVAPGTALRDGLERVLRGNTGGLIVLGTDKTVESLCTGGFVIDVEFTATRLRELCKLDGALVLDKDITKIVRAG
VQLVPDAAIPTEETGTRHRTAQRVSIQTGFPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIAGVEPERELVVRDYVPEPTAKRT
RTVTDALAELDRLTHAELLELPIVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGAIIERLVEHFGGLQKLLAASVDD
LQMVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=551995 LUV23_RS25645 WP_069873662.1 6284677..6285735(-) (disA) [Streptomyces sp. HNM0561]
ATGCGTGCCTCCCTGAGCGCGGTCGCGCCCGGCACGGCGCTGCGCGACGGCCTCGAGCGGGTTCTCCGGGGAAACACCGG
CGGGCTGATCGTGCTCGGCACCGACAAGACCGTCGAGTCGCTGTGTACCGGCGGCTTCGTCATCGACGTCGAGTTCACCG
CGACCCGGCTGCGCGAGCTGTGCAAGCTGGACGGCGCGCTGGTCCTCGACAAGGACATCACCAAGATCGTGCGGGCCGGG
GTGCAGCTGGTGCCCGACGCGGCGATCCCCACCGAGGAGACCGGCACCCGGCACCGCACCGCGCAGCGCGTCTCCATCCA
GACCGGGTTCCCGGTGGTCTCGGTCAGCCAGTCGATGCGGCTGATCGCGCTGTATGTGGACGGTCAGCGGCGGGTCCTGG
AGGATTCGGCGGCGATCCTGTCCCGCGCCAACCAGGCGCTGGCCACGCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTG
GCGGGCACGCTCTCGGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGATGTGAGCGCGGTCGCACAGCGGCTGGAGAT
GGTCCGCCGCATCGCCACCGAGATCGCGGAGTACGTGGTCGAGCTGGGCACCGACGGCCGGCTGCTCTCCCTCCAGCTGG
ACGAGCTGATCGCGGGCGTGGAGCCGGAGCGTGAGCTGGTGGTGCGGGACTACGTCCCCGAGCCGACCGCCAAGCGCACC
CGTACGGTGACCGACGCGCTCGCCGAGCTGGACCGGCTGACCCACGCCGAGCTGCTCGAACTCCCCATCGTGGCCCGGGC
GCTGGGGTACACCGGCTCGCCCGAGACCCTCGACTCGGCGGTCTCGCCGCGCGGCTTCCGGCTGCTGGCGAAGGTGCCGC
GGCTTCCGGGCGCCATCATCGAGCGGCTCGTGGAGCACTTCGGGGGCTTGCAGAAGCTGCTGGCGGCGAGCGTGGACGAC
CTCCAGATGGTGGACGGCGTGGGCGAGGCCCGCGCGCGCTCGGTCCGCGAGGGCCTGTCGCGGCTGGCCGAGTCGTCCAT
CCTGGAGCGGTACGTCTAG

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(133-275)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(16-129)

Helix-hairpin-helix motif (HHH_2)

(302-337)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X2M0H5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

47.11

98.295

0.463