Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ANG_RS08860 Genome accession   NZ_AP013072
Coordinates   1763261..1763893 (-) Length   210 a.a.
NCBI ID   WP_003036430.1    Uniprot ID   I0SDI7
Organism   Streptococcus anginosus subsp. whileyi MAS624     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1758261..1768893
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ANG_RS08835 (ANG_1798) recX 1759486..1760262 (+) 777 WP_003036445.1 recombination regulator RecX -
  ANG_RS08840 (ANG_1799) - 1760349..1760882 (+) 534 WP_003031472.1 DUF402 domain-containing protein -
  ANG_RS08845 (ANG_1800) - 1761002..1761319 (+) 318 WP_003036352.1 DUF960 domain-containing protein -
  ANG_RS08850 (ANG_1801) - 1761445..1761819 (-) 375 WP_020999484.1 S1 RNA-binding domain-containing protein -
  ANG_RS08855 (ANG_1802) - 1761821..1763221 (-) 1401 WP_003036370.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ANG_RS08860 (ANG_1803) vraR 1763261..1763893 (-) 633 WP_003036430.1 response regulator transcription factor Regulator
  ANG_RS08865 (ANG_1804) - 1763895..1764890 (-) 996 WP_003036415.1 sensor histidine kinase -
  ANG_RS08870 (ANG_1805) liaF 1764887..1765585 (-) 699 WP_003036398.1 cell wall-active antibiotics response protein LiaF -
  ANG_RS08875 (ANG_1806) stkP 1765846..1767720 (-) 1875 WP_003036358.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ANG_RS08880 (ANG_1807) - 1767717..1768457 (-) 741 WP_003036337.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23698.31 Da        Isoelectric Point: 4.9093

>NTDB_id=55138 ANG_RS08860 WP_003036430.1 1763261..1763893(-) (vraR) [Streptococcus anginosus subsp. whileyi MAS624]
MHILLVDDHEMVRLGLKGYLDLQDDVDVVAEASNGREGVEKALELRPDVIMMDIVMPEMSGIKATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=55138 ANG_RS08860 WP_003036430.1 1763261..1763893(-) (vraR) [Streptococcus anginosus subsp. whileyi MAS624]
ATGCATATTTTATTAGTAGATGACCATGAAATGGTACGACTTGGCTTGAAAGGTTATTTGGATTTACAAGACGATGTGGA
TGTAGTGGCAGAAGCTTCAAATGGTCGCGAAGGAGTTGAAAAAGCTTTGGAGTTGCGCCCAGATGTGATTATGATGGACA
TTGTTATGCCTGAAATGAGTGGGATTAAAGCGACACTTGCTATTTTAAAAGAATGGCCTGAAGCTAAAATTCTCATTTTG
ACTTCTTATTTGGATAATGAAAAAATTTATCCGGTTTTAGACGCAGGTGCTAAAGGATATATGCTGAAAACATCTAGTGC
TGATGATATTTTACGAGCTGTCCGAAAAGTAGCTAAGGGTGAACTTGCCATTGAAACAGAGGTCAGCCAAAAAGTGGAAT
ATCATCGAAATCATATTGAATTGCACGAAGATTTGACTGCGCGTGAGCGAGATATTTTAGGACTACTGGCAAAAGGTTAT
GAAAATCAACGCATAGCAGATGAATTATTTATTTCTTTAAAGACAGTGAAAACACATGTGTCCAATATCTTATCAAAGCT
AGAAGTGAGCGATCGTACACAAGCTGTTGTTTATGCTTTCCAACATCACCTTGTCCCACAAGATGACATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SDI7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment