Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   B938_RS05825 Genome accession   NC_019842
Coordinates   1138402..1139058 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis AS43.3     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1133402..1144058
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B938_RS05800 (B938_05570) oppF 1133931..1134848 (+) 918 WP_015239568.1 oligopeptide ABC transporter ATP-binding protein OppF -
  B938_RS05805 (B938_05575) - 1134955..1136142 (+) 1188 WP_015239569.1 putative glycoside hydrolase -
  B938_RS05810 (B938_05580) - 1136260..1136838 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  B938_RS05815 (B938_05585) spx 1137017..1137412 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  B938_RS05820 (B938_05590) - 1137470..1138126 (-) 657 WP_015239570.1 TerC family protein -
  B938_RS20560 - 1138309..1138419 (+) 111 Protein_1094 adaptor protein MecA -
  B938_RS05825 (B938_05595) mecA 1138402..1139058 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  B938_RS05830 (B938_05600) - 1139209..1140368 (+) 1160 Protein_1096 competence protein CoiA family protein -
  B938_RS05835 (B938_05605) pepF 1140596..1142425 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  B938_RS20195 (B938_05610) - 1142464..1142631 (-) 168 WP_003155026.1 hypothetical protein -
  B938_RS05850 (B938_05620) spxH 1142917..1143819 (-) 903 WP_015239573.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=55138 B938_RS05825 WP_003155032.1 1138402..1139058(+) (mecA) [Bacillus velezensis AS43.3]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=55138 B938_RS05825 WP_003155032.1 1138402..1139058(+) (mecA) [Bacillus velezensis AS43.3]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment