Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ANG_RS01200 Genome accession   NZ_AP013072
Coordinates   225750..227696 (+) Length   648 a.a.
NCBI ID   WP_025271565.1    Uniprot ID   -
Organism   Streptococcus anginosus subsp. whileyi MAS624     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 220750..232696
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ANG_RS11145 (ANG_0211) - 220767..220943 (-) 177 WP_003027795.1 hypothetical protein -
  ANG_RS01170 (ANG_0212) - 220940..221218 (-) 279 WP_003027794.1 hypothetical protein -
  ANG_RS11150 (ANG_0213) - 221561..221728 (-) 168 WP_003038324.1 hypothetical protein -
  ANG_RS01175 (ANG_0214) - 221732..222349 (-) 618 WP_003038403.1 Rha family transcriptional regulator -
  ANG_RS01180 (ANG_0215) - 222366..222563 (-) 198 WP_003038356.1 helix-turn-helix domain-containing protein -
  ANG_RS10695 (ANG_0216) - 222725..223201 (+) 477 WP_003038410.1 helix-turn-helix domain-containing protein -
  ANG_RS01190 (ANG_0217) - 223346..224350 (+) 1005 WP_003038394.1 virulence RhuM family protein -
  ANG_RS01195 (ANG_0218) - 224507..225655 (+) 1149 WP_003038317.1 tyrosine-type recombinase/integrase -
  ANG_RS01200 (ANG_0219) hexB 225750..227696 (+) 1947 WP_025271565.1 DNA mismatch repair endonuclease MutL Machinery gene
  ANG_RS01205 - 228171..228509 (-) 339 WP_003038373.1 hypothetical protein -
  ANG_RS01210 (ANG_0220) ruvA 228608..229198 (+) 591 WP_003038332.1 Holliday junction branch migration protein RuvA Machinery gene
  ANG_RS01215 (ANG_0221) - 229209..229781 (+) 573 WP_003038379.1 DNA-3-methyladenine glycosylase I -
  ANG_RS01220 - 229890..230303 (-) 414 Protein_220 EamA family transporter -
  ANG_RS01225 (ANG_0223) cinA 230901..232169 (+) 1269 WP_003038347.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 648 a.a.        Molecular weight: 73194.30 Da        Isoelectric Point: 5.0580

>NTDB_id=55063 ANG_RS01200 WP_025271565.1 225750..227696(+) (hexB) [Streptococcus anginosus subsp. whileyi MAS624]
MSKIIELPENLANQIAAGEVIERPSSVVKELIENSIDAGATQIIVEIEEAGLRSIQVIDNGEGIEHEEVSLALRRHATSK
IKKQADLFRIRTLGFRGEALPSIASVSRLTIETATSSGAHGTLLIAQGGEVETLDPSSCPRGTKIKVEDLFFNTPARLKY
MKSQQAELSHIVDVINRLSLAHPEVAFTLVNDGKEMTRTAGTGNLRQAIAGIYGLTTAKKMIEILASDLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIRIDPYLADVNVHPTKQEVRISKERELMALISQ
AIAVSLKEQDLIPDALENLAKSTINRAIKPEQTSLPLKENRLYYDKERNDFFVKPQVSEAQPSFEESARLDQQSADTDEL
NSKSASVKFAERQSPSYNQLDHPELDQASLERALDKLDGEETSTFPELEYFGQMHGTYLFAQGNGGLYIIDQHAAQERVK
YEYYREKIGDVDASQQQLLVPYIFEFPADDMLRLKQRMSLLEEAGVFLEEYGTNQFILREHPIWLKEEEIESGIYEMCDM
LLLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLIFQLSQCDNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHT
SLRELGKY

Nucleotide


Download         Length: 1947 bp        

>NTDB_id=55063 ANG_RS01200 WP_025271565.1 225750..227696(+) (hexB) [Streptococcus anginosus subsp. whileyi MAS624]
ATGTCAAAAATTATTGAACTACCAGAAAATCTTGCTAATCAGATTGCAGCGGGTGAGGTTATTGAGCGACCTAGCAGCGT
TGTCAAGGAGTTAATAGAAAATTCTATTGATGCTGGTGCCACTCAGATTATAGTTGAGATTGAAGAAGCGGGACTCAGGA
GCATTCAAGTCATTGATAATGGTGAAGGAATTGAGCATGAGGAGGTTTCCTTGGCTTTGCGGCGGCATGCTACTAGTAAA
ATCAAGAAACAAGCCGACCTTTTTCGAATTCGGACATTGGGCTTTCGGGGCGAGGCGCTTCCATCCATTGCCTCTGTTTC
ACGTTTGACGATTGAAACTGCGACAAGTAGTGGTGCACATGGAACGCTTCTGATTGCGCAAGGTGGAGAAGTTGAGACTT
TAGATCCAAGTAGCTGTCCTAGGGGTACCAAAATCAAAGTGGAAGACCTTTTTTTCAACACGCCTGCTCGCTTGAAATAT
ATGAAAAGCCAACAAGCGGAACTATCTCATATTGTAGATGTGATTAACCGTTTAAGCTTGGCTCATCCGGAGGTCGCTTT
CACTCTTGTTAATGACGGTAAAGAGATGACACGGACAGCAGGAACAGGAAATCTGCGTCAAGCAATTGCTGGTATTTATG
GACTGACAACAGCCAAAAAAATGATTGAAATTTTAGCATCTGATTTGGATTTTGAAGTATCAGGCTATATTAGTTTGCCA
GAATTAACAAGGGCTAATCGGAATTACATTACTATCCTCATCAATGGTCGCTACATCAAGAATTTCCTACTCAATCGAGC
TATTTTAGATGGATATGGTAGCAAGCTCATGGTGGGACGTTTCCCGATTGCTGTGATTGATATTCGGATTGACCCATATC
TTGCTGATGTTAATGTTCACCCGACCAAGCAAGAAGTGCGGATTTCAAAGGAGCGAGAGCTCATGGCCTTGATATCGCAA
GCTATTGCTGTAAGTTTGAAAGAGCAAGATTTGATTCCGGACGCATTAGAGAATTTAGCCAAATCAACCATTAACCGAGC
AATTAAGCCTGAGCAGACCAGCCTCCCTCTCAAAGAGAACCGACTTTATTACGATAAAGAAAGAAATGACTTCTTTGTGA
AACCACAAGTGTCAGAAGCTCAACCTTCTTTTGAGGAATCTGCCCGATTAGACCAACAATCTGCTGATACAGATGAACTC
AATTCAAAATCTGCTTCTGTCAAATTTGCAGAAAGGCAATCTCCTTCTTACAATCAACTAGATCATCCAGAGCTGGATCA
GGCGAGCTTAGAGAGAGCTTTAGATAAGCTAGATGGAGAAGAAACTTCAACGTTTCCAGAATTGGAATATTTCGGGCAAA
TGCACGGCACCTACCTTTTTGCTCAAGGAAACGGTGGCCTTTATATTATTGACCAACATGCAGCTCAAGAGCGAGTAAAG
TACGAATATTACCGCGAAAAAATCGGAGATGTAGATGCTAGTCAGCAGCAGCTTCTGGTTCCCTATATTTTTGAATTTCC
AGCCGATGATATGCTGCGTCTGAAACAACGGATGTCTCTTTTAGAAGAAGCCGGTGTTTTCCTTGAAGAATACGGAACTA
ATCAATTTATTCTTCGTGAACATCCCATTTGGCTTAAGGAAGAGGAGATCGAATCAGGTATTTATGAGATGTGCGATATG
CTCCTTCTAACCAAGGAAGTCTCTATCAAGAAATATCGCGCTGAGCTGGCTATTATGATGAGTTGCAAACGCTCTATTAA
AGCCAATCACAGTTTGGATGACTATTCAGCGCGTGATTTGATCTTCCAGCTATCACAATGCGATAATCCCTACAACTGCC
CTCACGGTCGTCCCGTTTTGGTCAACTTCACCAAATCTGATATGGAAAAAATGTTCCGTCGGATTCAGGAAAATCATACC
AGCCTGAGAGAATTGGGGAAATATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(450-592)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-116)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-325)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

77.042

100

0.772

Multiple sequence alignment