Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   J5M87_RS07685 Genome accession   NZ_CP072115
Coordinates   1637217..1637909 (-) Length   230 a.a.
NCBI ID   WP_154608315.1    Uniprot ID   A0A6I4RA32
Organism   Streptococcus zhangguiae strain zg-86     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1632217..1642909
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5M87_RS07660 (J5M87_07660) - 1632249..1632962 (-) 714 WP_154608311.1 NADPH-dependent oxidoreductase -
  J5M87_RS07665 (J5M87_07665) dnaI 1632959..1633858 (-) 900 WP_154608312.1 primosomal protein DnaI -
  J5M87_RS07670 (J5M87_07670) - 1633859..1635010 (-) 1152 WP_154608313.1 DnaD domain protein -
  J5M87_RS07675 (J5M87_07675) nrdR 1635019..1635486 (-) 468 WP_067086351.1 transcriptional regulator NrdR -
  J5M87_RS07680 (J5M87_07680) - 1635597..1636727 (-) 1131 WP_154608314.1 AI-2E family transporter -
  J5M87_RS07685 (J5M87_07685) covR 1637217..1637909 (-) 693 WP_154608315.1 response regulator transcription factor Regulator
  J5M87_RS07690 (J5M87_07690) gndA 1637913..1639337 (-) 1425 WP_154608316.1 NADP-dependent phosphogluconate dehydrogenase -
  J5M87_RS07695 (J5M87_07695) - 1639425..1639961 (-) 537 WP_154608317.1 DUF177 domain-containing protein -
  J5M87_RS07700 (J5M87_07700) trxB 1639972..1640889 (-) 918 WP_154608318.1 thioredoxin-disulfide reductase -
  J5M87_RS07705 (J5M87_07705) - 1640912..1641136 (-) 225 WP_154608319.1 DUF4059 family protein -
  J5M87_RS07710 (J5M87_07710) - 1641166..1642509 (-) 1344 WP_154608320.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26601.64 Da        Isoelectric Point: 6.0414

>NTDB_id=550549 J5M87_RS07685 WP_154608315.1 1637217..1637909(-) (covR) [Streptococcus zhangguiae strain zg-86]
MVKKILIAGRERNLSHFVSMELQKKDYLVDYASTGKEALLLAHETDFDLILMSFQLSDMSSHDLATELLTIKPSMVMIVV
VDSEDAKEHGVAIQRYAVSYIIKPFVISDLVDQVTSIFRGRDYIDEHCKQVKLQAAYRDVKIDFQNRTVTRGREPINLTR
REYDLLATLMNSQEILTREQLLERVWKYEAAAETNVVDVYIRYLRGKLDLPGQESYIKTIRGVGYAMREE

Nucleotide


Download         Length: 693 bp        

>NTDB_id=550549 J5M87_RS07685 WP_154608315.1 1637217..1637909(-) (covR) [Streptococcus zhangguiae strain zg-86]
ATGGTAAAAAAAATCTTAATTGCAGGTCGGGAGCGCAATCTATCTCATTTTGTGTCCATGGAGTTGCAAAAAAAAGACTA
CTTGGTGGACTATGCTTCAACAGGAAAAGAAGCGCTTCTGCTTGCCCATGAGACGGATTTTGATTTGATTCTCATGAGTT
TTCAGCTGTCAGACATGTCAAGCCATGATTTGGCGACTGAATTGTTGACAATCAAACCGTCAATGGTCATGATTGTTGTC
GTGGATAGTGAGGATGCGAAAGAGCATGGTGTTGCGATTCAACGCTATGCGGTTTCCTATATTATCAAGCCCTTTGTCAT
TAGTGATTTGGTTGATCAGGTGACGTCTATCTTTAGAGGGCGGGATTATATTGATGAACATTGTAAACAAGTCAAGCTCC
AAGCAGCTTATCGTGATGTAAAGATTGATTTTCAAAATCGCACGGTGACCCGTGGCCGAGAACCAATCAATCTGACCCGT
CGTGAATATGATCTTCTTGCGACCTTGATGAATAGTCAAGAAATTCTAACTCGTGAGCAATTGCTAGAACGAGTTTGGAA
GTATGAAGCAGCAGCAGAAACCAATGTCGTGGATGTCTATATACGCTATCTGCGTGGAAAATTAGACTTGCCAGGTCAAG
AATCCTATATTAAAACAATTCGCGGTGTTGGTTACGCCATGCGAGAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I4RA32

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.927

100

0.496
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.978

99.565

0.448