Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   J5M87_RS06665 Genome accession   NZ_CP072115
Coordinates   1395759..1396511 (-) Length   250 a.a.
NCBI ID   WP_154608411.1    Uniprot ID   A0A6I4RCR3
Organism   Streptococcus zhangguiae strain zg-86     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1390759..1401511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5M87_RS06640 (J5M87_06640) - 1391149..1391514 (-) 366 WP_181351490.1 hypothetical protein -
  J5M87_RS06645 (J5M87_06645) - 1391587..1391793 (-) 207 WP_154608776.1 hypothetical protein -
  J5M87_RS06650 (J5M87_06650) - 1391839..1392168 (-) 330 WP_154608775.1 helicase BlpT -
  J5M87_RS06655 (J5M87_06655) - 1392733..1394553 (+) 1821 WP_348271965.1 IS1182 family transposase -
  J5M87_RS06660 (J5M87_06660) - 1394494..1395762 (-) 1269 Protein_1279 sensor histidine kinase -
  J5M87_RS06665 (J5M87_06665) comE/blpR 1395759..1396511 (-) 753 WP_154608411.1 response regulator transcription factor Regulator
  J5M87_RS06670 (J5M87_06670) cls 1396684..1398231 (-) 1548 WP_154608412.1 cardiolipin synthase -
  J5M87_RS06675 (J5M87_06675) - 1399059..1399814 (-) 756 WP_160463258.1 SDR family oxidoreductase -
  J5M87_RS06680 (J5M87_06680) rnz 1399811..1400740 (-) 930 WP_154608413.1 ribonuclease Z -
  J5M87_RS06685 (J5M87_06685) - 1400751..1401377 (-) 627 WP_154608414.1 cystathionine beta-lyase -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29034.40 Da        Isoelectric Point: 5.8720

>NTDB_id=550542 J5M87_RS06665 WP_154608411.1 1395759..1396511(-) (comE/blpR) [Streptococcus zhangguiae strain zg-86]
MNIFILEDDVVQQSRMEEVVAGLIAQHHLSVKRLEVFGKPEQLLAAVEEKGRHQLFFLDIEIREEEKKGLEVAREIRQLD
PYAMIVFVTTHSEWMPLAFRYQVSALDYIAKNLPSDEWLARIEKVLLYADEQVTKTVAEDAFYYQSKYAQIQVPFQDILY
LETSPRPHRVILYTEKDRTEFTASLAEVLQQEPRLLACHRSFVVNPANVVKIDKHEKILYFRNGSSCWIARSKLETVLAT
IEQLHKGSGL

Nucleotide


Download         Length: 753 bp        

>NTDB_id=550542 J5M87_RS06665 WP_154608411.1 1395759..1396511(-) (comE/blpR) [Streptococcus zhangguiae strain zg-86]
ATGAATATTTTTATACTGGAAGATGATGTTGTTCAACAATCTCGAATGGAAGAAGTCGTAGCGGGTCTTATAGCCCAGCA
CCACTTATCGGTCAAGCGGCTAGAGGTGTTTGGTAAGCCAGAACAATTGCTAGCAGCAGTAGAGGAAAAGGGACGTCATC
AGCTTTTCTTTTTAGATATTGAAATCAGAGAGGAAGAAAAAAAGGGACTCGAAGTGGCGCGTGAGATTCGTCAGCTCGAT
CCCTATGCGATGATTGTCTTTGTGACCACTCATTCTGAATGGATGCCCTTGGCTTTTCGCTACCAAGTGTCTGCTCTTGA
CTATATCGCCAAGAATCTCCCTTCTGATGAATGGCTAGCTCGAATCGAGAAAGTGCTTCTATATGCAGATGAGCAAGTGA
CAAAGACAGTGGCGGAGGATGCTTTTTATTATCAGTCCAAGTATGCGCAGATTCAGGTTCCGTTTCAGGACATCCTGTAT
TTAGAAACCTCCCCTCGCCCGCATCGTGTCATTTTGTATACGGAAAAGGATCGCACAGAGTTTACCGCTAGTTTAGCAGA
AGTCTTGCAACAGGAACCAAGGCTCCTTGCCTGTCATCGTTCCTTTGTCGTCAATCCAGCCAATGTTGTCAAAATTGATA
AGCATGAAAAAATTCTCTATTTTCGCAATGGCTCTAGTTGTTGGATTGCAAGAAGTAAGTTAGAGACGGTACTAGCTACG
ATTGAACAGTTACATAAAGGAAGTGGCCTATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I4RCR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.479

96.8

0.508
  comE/comE1 Streptococcus equinus JB1

44.351

95.6

0.424