Detailed information NTG0550539

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: J5M87_RS04995
• Genome accession: NZ_CP072115
• Coordinates: 1039274..1040116 (-)
• Length: 280 a.a.
• NCBI ID: WP_154607913.1
• Uniprot ID: A0A6I4R8K5
• Organism: Streptococcus zhangguiae strain zg-86
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1034274..1045116

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J5M87_RS04985 (J5M87_04985)	trmFO	1035446..1036786 (-)	1341	WP_154607911.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
J5M87_RS04990 (J5M87_04990)	topA	1037088..1039172 (-)	2085	WP_154607912.1	type I DNA topoisomerase	-
J5M87_RS04995 (J5M87_04995)	dprA	1039274..1040116 (-)	843	WP_154607913.1	DNA-processing protein DprA	Machinery gene
J5M87_RS05000 (J5M87_05000)	-	1040587..1041141 (-)	555	WP_154607914.1	sugar O-acetyltransferase	-
J5M87_RS05005 (J5M87_05005)	-	1041128..1041919 (-)	792	WP_154607915.1	ribonuclease HII	-
J5M87_RS05010 (J5M87_05010)	ylqF	1041906..1042757 (-)	852	WP_154607916.1	ribosome biogenesis GTPase YlqF	-
J5M87_RS05015 (J5M87_05015)	-	1043298..1044236 (-)	939	WP_154607917.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31013.05 Da
• Isoelectric Point: 9.2439

>NTDB_id=550539 J5M87_RS04995 WP_154607913.1 1039274..1040116(-) (dprA) [Streptococcus zhangguiae strain zg-86]
MNNFELFTLKKAGLTNLQIHKVLATQDSHKKSLSLKSIALYSTCKNPVIFIEKYKQLDLKRCREEFNRFPSFSILDEIYP
LELKQMYNPPVLLFYQGDLSLLEHPKLGVVGARSASSMGTQSIKKIISELNNRFVIVSGLARGIDTAAHMATLKNGGKTI
AVIGSGLAVHYPKENAVLQRYLAREHLLLTEYAADTPPLKYHFPERNRIIAGLSQGIVVAEAKMRSGSLITCERALEEGR
DVFAIPGSILDGKTAGCHHLIQEGAKCITSGLDVLSEYQI

Nucleotide

• Length: 843 bp

>NTDB_id=550539 J5M87_RS04995 WP_154607913.1 1039274..1040116(-) (dprA) [Streptococcus zhangguiae strain zg-86]
ATGAATAACTTTGAATTATTTACATTAAAAAAAGCAGGATTGACGAATCTGCAAATCCATAAGGTATTGGCGACTCAAGA
TAGTCATAAAAAATCATTATCGCTTAAATCAATAGCTCTTTACTCCACGTGTAAAAATCCTGTCATATTCATCGAAAAAT
ATAAACAGCTGGATCTCAAAAGATGTCGAGAGGAGTTTAATCGCTTTCCTTCTTTTTCCATTTTAGATGAGATTTATCCA
TTAGAGCTAAAACAGATGTATAACCCACCGGTTTTGCTGTTTTATCAGGGAGATCTTAGTTTGTTGGAACATCCTAAACT
TGGAGTAGTTGGAGCCCGTTCAGCAAGTTCAATGGGTACTCAGTCAATCAAAAAAATCATCAGCGAATTGAACAACCGTT
TTGTCATTGTCAGTGGTTTAGCTAGGGGAATTGATACAGCAGCGCACATGGCTACTTTAAAAAATGGTGGTAAGACAATA
GCTGTTATCGGATCGGGGCTAGCGGTCCATTATCCGAAAGAAAATGCCGTTTTACAGCGTTATCTTGCACGCGAACACTT
ACTGCTTACCGAATATGCTGCAGATACGCCACCCTTAAAATATCATTTTCCTGAGCGTAATCGGATTATTGCAGGTTTGT
CACAAGGAATTGTCGTAGCAGAAGCAAAAATGAGGTCAGGAAGCTTGATTACCTGTGAGAGAGCTTTAGAAGAAGGACGA
GATGTTTTTGCTATTCCAGGATCTATTTTGGACGGAAAAACTGCTGGTTGTCATCATTTGATTCAAGAGGGTGCAAAGTG
CATTACATCAGGCCTTGATGTCCTTTCCGAGTATCAAATTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

3D structure

• AlphaFold DB: A0A6I4R8K5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	69.286	100	0.693
dprA/cilB/dalA	Streptococcus mitis SK321	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae D39	61.429	100	0.614
dprA/cilB/dalA	Streptococcus pneumoniae R6	61.429	100	0.614
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	61.429	100	0.614
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	61.429	100	0.614
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.714	100	0.607
dprA	Lactococcus lactis subsp. cremoris KW2	55.755	99.286	0.554
dprA	Latilactobacillus sakei subsp. sakei 23K	42.353	91.071	0.386