Detailed information NTG0550479

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: J5Z97_RS03725
• Genome accession: NZ_CP072112
• Coordinates: 727882..729111 (+)
• Length: 409 a.a.
• NCBI ID: WP_009880296.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain M08500
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 722882..734111

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J5Z97_RS03700 (J5Z97_03700)	-	723498..724775 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
J5Z97_RS03705 (J5Z97_03705)	-	724762..725937 (-)	1176	WP_047235862.1	hydroxymethylglutaryl-CoA synthase	-
J5Z97_RS03710 (J5Z97_03710)	-	726146..726985 (+)	840	WP_011017679.1	thymidylate synthase	-
J5Z97_RS03715 (J5Z97_03715)	-	727065..727562 (+)	498	WP_002984955.1	dihydrofolate reductase	-
J5Z97_RS03720 (J5Z97_03720)	-	727582..727752 (+)	171	WP_002990165.1	hypothetical protein	-
J5Z97_RS03725 (J5Z97_03725)	clpX	727882..729111 (+)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
J5Z97_RS03730 (J5Z97_03730)	yihA	729121..729720 (+)	600	WP_023611144.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
J5Z97_RS03735 (J5Z97_03735)	-	729868..730611 (+)	744	WP_002984942.1	hypothetical protein	-
J5Z97_RS03740 (J5Z97_03740)	-	730669..732768 (-)	2100	WP_023611120.1	ATP-dependent Clp protease ATP-binding subunit	-
J5Z97_RS03745 (J5Z97_03745)	rpiA	733147..733830 (+)	684	WP_009881270.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45020.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=550479 J5Z97_RS03725 WP_009880296.1 727882..729111(+) (clpX) [Streptococcus pyogenes strain M08500]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=550479 J5Z97_RS03725 WP_009880296.1 727882..729111(+) (clpX) [Streptococcus pyogenes strain M08500]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGACGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCGATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575