Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LSG45_RS12450 Genome accession   NZ_CP089238
Coordinates   2629804..2630448 (+) Length   214 a.a.
NCBI ID   WP_003090351.1    Uniprot ID   A0A0H2ZC55
Organism   Pseudomonas aeruginosa strain JNQH-PA033     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2624804..2635448
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LSG45_RS12435 (LSG45_12435) - 2625441..2626655 (+) 1215 WP_234575649.1 MFS transporter -
  LSG45_RS12440 (LSG45_12440) - 2626671..2627699 (-) 1029 WP_023435195.1 AraC family transcriptional regulator -
  LSG45_RS12445 (LSG45_12445) pqsH 2628314..2629462 (+) 1149 WP_023125848.1 2-heptyl-3-hydroxy-4(1H)-quinolone synthase -
  LSG45_RS12450 (LSG45_12450) letA 2629804..2630448 (+) 645 WP_003090351.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LSG45_RS12455 (LSG45_12455) uvrC 2630449..2632275 (+) 1827 WP_031638071.1 excinuclease ABC subunit UvrC -
  LSG45_RS12460 (LSG45_12460) pgsA 2632309..2632869 (+) 561 WP_003090349.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LSG45_RS12470 (LSG45_12470) - 2633738..2634598 (-) 861 WP_225011024.1 fimbrial protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23608.53 Da        Isoelectric Point: 6.1073

>NTDB_id=549795 LSG45_RS12450 WP_003090351.1 2629804..2630448(+) (letA) [Pseudomonas aeruginosa strain JNQH-PA033]
MIKVLVVDDHDLVRTGITRMLADIEGLQVVGQADCGEDCLKLARELKPDVVLMDVKMPGIGGLEATRKLLRSQPDIKVVV
VTVCEEDPFPTRLMQAGAAGYMTKGAGLEEMVQAIRQVFAGQRYISPQIAQQLALKSFQPQQHDSPFDSLSEREIQIALM
IANCHKVQSISDKLCLSPKTVNTYRYRIFEKLSITSDVELALLAVRHGMVDAAS

Nucleotide


Download         Length: 645 bp        

>NTDB_id=549795 LSG45_RS12450 WP_003090351.1 2629804..2630448(+) (letA) [Pseudomonas aeruginosa strain JNQH-PA033]
GTGATTAAGGTGCTGGTGGTCGACGACCACGATCTGGTACGCACCGGTATTACCCGCATGCTGGCCGACATCGAAGGCTT
GCAAGTGGTCGGCCAGGCCGACTGCGGTGAAGACTGTCTGAAACTGGCCCGCGAGCTGAAGCCGGATGTCGTCCTGATGG
ACGTGAAGATGCCCGGTATCGGCGGCTTGGAGGCGACCCGCAAGCTGCTGCGCAGCCAGCCCGACATCAAGGTCGTGGTA
GTCACCGTCTGCGAAGAGGACCCGTTCCCCACCCGCCTCATGCAGGCCGGCGCCGCCGGCTACATGACCAAGGGCGCGGG
GCTGGAGGAAATGGTCCAGGCGATTCGCCAGGTCTTCGCCGGCCAGCGCTACATCAGCCCGCAGATCGCCCAGCAACTGG
CGCTGAAGTCCTTCCAGCCGCAGCAGCACGATTCCCCCTTCGATTCGCTGTCCGAGCGCGAGATCCAGATCGCCCTGATG
ATCGCCAACTGCCACAAGGTGCAGAGCATCTCCGACAAGCTGTGCCTGTCGCCGAAGACCGTGAATACCTATCGCTACCG
CATCTTCGAGAAGCTCTCGATCACCAGCGACGTGGAACTGGCGCTGCTCGCCGTCCGCCACGGCATGGTCGATGCCGCCA
GCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZC55

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

54.502

98.598

0.537
  letA Legionella pneumophila strain ERS1305867

54.502

98.598

0.537