Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   J4Z26_RS00180 Genome accession   NZ_CP071988
Coordinates   48619..49968 (-) Length   449 a.a.
NCBI ID   WP_049371013.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain CBPA-ST-10002 isolate HPB10235     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 43619..54968
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4Z26_RS00160 (J4Z26_000032) - 45228..45740 (-) 513 WP_049371005.1 DUF1643 domain-containing protein -
  J4Z26_RS00165 (J4Z26_000033) - 45756..46064 (-) 309 WP_049371007.1 DUF960 family protein -
  J4Z26_RS00170 (J4Z26_000034) - 46149..46499 (-) 351 WP_049371009.1 SAUGI family uracil-DNA glycosylase inhibitor -
  J4Z26_RS00175 (J4Z26_000035) ccrB 46970..48598 (-) 1629 WP_049371011.1 cassette chromosome recombinase CcrB Machinery gene
  J4Z26_RS00180 (J4Z26_000036) ccrA 48619..49968 (-) 1350 WP_049371013.1 cassette chromosome recombinase CcrA Machinery gene
  J4Z26_RS00185 (J4Z26_000037) - 50146..50403 (-) 258 WP_049371015.1 hypothetical protein -
  J4Z26_RS00190 (J4Z26_000038) cch1 50468..52258 (-) 1791 WP_049387333.1 cassette chromosome replicative helicase -
  J4Z26_RS00195 (J4Z26_000039) ssb 52258..52551 (-) 294 WP_037576829.1 cassette chromosome ssDNA-binding protein -
  J4Z26_RS00200 (J4Z26_000040) - 52723..54234 (-) 1512 WP_049371020.1 hypothetical protein -
  J4Z26_RS00205 (J4Z26_000041) - 54296..54961 (-) 666 WP_049371022.1 Cthe_2314 family HEPN domain-containing protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52282.83 Da        Isoelectric Point: 9.9669

>NTDB_id=549766 J4Z26_RS00180 WP_049371013.1 48619..49968(-) (ccrA) [Staphylococcus epidermidis strain CBPA-ST-10002 isolate HPB10235]
MKQAMGYLRQSTTKQQSLAAQKQTIKVLAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKAKQGKLITTHAPFGYHYH
NGTFTIDTVKSPTVKAVFNYYLQGYGYKKIAQYLEADDKFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEEAQVTRTQKQVKRKPSENQLKQKIKCPYCHSTLTNMTVRKPDYSLRYYVCPQNMNNARFVCEFKGINAQELETSVLAT
CQDFFQNQQLYSKINHTIQQRLKRQRDVETKTALNHEQLIEKLAQGKIDAETFREQTRSLHQQSKPLSSISAYQSRNAFQ
NIIQQRFTLNMLNPYIDVISITKNKTLAGIYFKNEPLNIVNQTTQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=549766 J4Z26_RS00180 WP_049371013.1 48619..49968(-) (ccrA) [Staphylococcus epidermidis strain CBPA-ST-10002 isolate HPB10235]
ATGAAACAAGCAATGGGTTACTTACGACAGAGCACTACAAAGCAACAATCCTTAGCAGCACAAAAACAAACCATCAAGGT
ATTAGCCGAAAAACATAATATTCAACACATTACCTTTTATAGCGATAAACAATCAGGACGTACTGATAAGCGGAATGGTT
ATCAACAAATTACTGAACTGATTCAACAGGGACAATGTGACGTATTATGTTGCTATCGTCTAAATCGACTTCATCGTAAT
TTGAAAAATGCATTAAAACTCATGAAATTGTGTCAAAAATACCATGTCCATATCTTAAGCGTTCATGATGGCTACTTCGA
CATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCTGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAAACAAGGTAAACTGATTACAACACATGCACCCTTTGGGTATCACTATCAT
AATGGTACTTTCACGATAGACACAGTAAAATCACCAACAGTAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATGATAAATTCATTAATCGCAAGCCCTATCAAGTGCGTAATATTATCCTTA
ACCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TACGAAGAAGCTCAAGTTACCCGAACTCAGAAACAAGTCAAACGTAAGCCGTCAGAAAATCAACTCAAACAAAAAATCAA
ATGTCCCTATTGTCATTCGACACTCACAAACATGACTGTCCGCAAACCAGATTATTCATTGCGTTACTATGTCTGTCCGC
AAAATATGAATAACGCTCGCTTTGTTTGTGAATTTAAAGGAATCAACGCACAAGAATTAGAAACAAGTGTTTTAGCGACT
TGTCAGGACTTCTTTCAAAATCAACAGCTCTATTCAAAAATAAACCATACTATTCAACAACGACTCAAAAGACAAAGAGA
TGTAGAAACTAAAACTGCACTCAATCACGAGCAGCTGATAGAAAAATTAGCCCAAGGCAAAATTGATGCAGAAACGTTCA
GAGAACAAACGCGTTCATTACATCAACAATCAAAACCTTTATCATCAATCAGTGCGTATCAAAGTCGAAACGCTTTCCAA
AACATCATTCAACAACGTTTCACACTAAACATGCTGAATCCCTATATTGATGTAATTAGTATTACTAAAAACAAAACCCT
TGCGGGGATCTATTTCAAAAATGAACCTCTAAACATTGTCAATCAAACGACGCAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(170-249)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

92.205

100

0.922
  ccrA Staphylococcus aureus N315

74.165

100

0.742