Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   J5D25_RS00100 Genome accession   NZ_CP071986
Coordinates   14376..16739 (+) Length   787 a.a.
NCBI ID   WP_209553890.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5124     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9376..21739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D25_RS00070 (J5D25_00070) groES 9399..9755 (-) 357 WP_000671927.1 co-chaperone GroES -
  J5D25_RS00075 (J5D25_00075) dnaG 10038..11717 (+) 1680 WP_209553887.1 DNA primase -
  J5D25_RS00080 (J5D25_00080) - 11714..12766 (+) 1053 WP_209553888.1 MnmA/TRMU family protein -
  J5D25_RS00085 (J5D25_00085) - 12857..13684 (+) 828 WP_209553889.1 DUF5718 family protein -
  J5D25_RS00090 (J5D25_00090) comB2 13830..14111 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  J5D25_RS00095 (J5D25_00095) comB3 14111..14374 (+) 264 WP_000584973.1 hypothetical protein Machinery gene
  J5D25_RS00100 (J5D25_00100) comB4 14376..16739 (+) 2364 WP_209553890.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  J5D25_RS00110 (J5D25_00110) - 17044..18384 (+) 1341 WP_209554402.1 COG3014 family protein -
  J5D25_RS00115 (J5D25_00115) cheV1 18490..19455 (+) 966 WP_000785489.1 chemotaxis protein CheV1 -
  J5D25_RS00120 (J5D25_00120) nspC 19452..20669 (+) 1218 WP_209553891.1 carboxynorspermidine decarboxylase -
  J5D25_RS00125 (J5D25_00125) lpxE 20679..21212 (-) 534 WP_249936740.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90181.51 Da        Isoelectric Point: 7.4291

>NTDB_id=549727 J5D25_RS00100 WP_209553890.1 14376..16739(+) (comB4) [Helicobacter pylori strain MT5124]
MLEKLLGAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYQQSIQSDSQYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLNSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSAHKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNVLIKAPSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIYLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIDRVNGHTLVIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISGAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=549727 J5D25_RS00100 WP_209553890.1 14376..16739(+) (comB4) [Helicobacter pylori strain MT5124]
ATGTTAGAAAAGCTTTTAGGCGCTATCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCACGCCTGGTGGTTAAAAGGCGTAAAATTGATTATCAACAAAGCATTCAATCTGACTCTCA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAATAAAGAAGTGTATGAGAATCAGTATTTTTTAGTTTTAGAAAGCGCAC
ATTCCTTACAGGGCGTTTTAGAGCATAAGAAAAAATCTCTCATGCACGCTAATAGAGAAAATTTTAAGGATATTCTTTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCTTAGAAATCCAGCTCAAAAACTATGCCCCCAAACTCTTAAACTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAATGGGTTTGATCTCCCCTTAAAACCCCTAGTAGGGGGGTATTTGA
GCGACAGCTATATCGCTAGTTCCATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAACCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACTCC
ACTAGATATTATCTTTTCCATAGAGCCTATGAGCGCGCATAAAACACTGAGTTTTTTAAAGGAGAGGGCCAAGTTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAATTAGTCAAAACCAAACGATTATCCATGCAAAAATTCGCC
CTAAACGTTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACCAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATTTATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTGATGGTGTTTGAAAGGCAAAATTTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCATAATAACGCTAAAGAAATCGACAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCTTTTGACAGGATGCAAGGGCTG
TATTCTTTCACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAACCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTCGATCTCGCCCCTTCAAGAGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTGGTGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGATTTTAGTTTGCTGGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAACGTGATAAACCTAGACGCGATCACCCAAAACCCTAAAGATTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAGATCTTAGAAGAGTCCAGGAAAAACGACAGCGGCTTTTTGGTTTTTTTAGAC
GAATTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGACATTTACCAACTCAGTGGAGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTCATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACAACTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAATGGGAGCTCTAACATGATTGATGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAAATCTTTAATTCAGATTCTAGCCATGTCAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(424-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.205

100

0.972