Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   LTK19_RS12970 Genome accession   NZ_CP089156
Coordinates   2577048..2577821 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain UNC_SaCF35     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2572048..2582821
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LTK19_RS12950 (LTK19_12950) trmFO 2572391..2573698 (+) 1308 WP_000195263.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  LTK19_RS12955 (LTK19_12955) xerC 2574116..2575012 (+) 897 WP_001015609.1 tyrosine recombinase XerC -
  LTK19_RS12960 (LTK19_12960) hslV 2575009..2575554 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  LTK19_RS12965 (LTK19_12965) hslU 2575620..2577023 (+) 1404 WP_000379051.1 ATP-dependent protease ATPase subunit HslU -
  LTK19_RS12970 (LTK19_12970) codY 2577048..2577821 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  LTK19_RS12975 (LTK19_12975) - 2577872..2577964 (+) 93 WP_031788481.1 hypothetical protein -
  LTK19_RS12980 (LTK19_12980) rpsB 2578163..2578930 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  LTK19_RS12985 (LTK19_12985) - 2578964..2579077 (+) 114 WP_001791405.1 hypothetical protein -
  LTK19_RS12990 (LTK19_12990) tsf 2579112..2579993 (+) 882 WP_000201387.1 translation elongation factor Ts -
  LTK19_RS12995 (LTK19_12995) pyrH 2580130..2580852 (+) 723 WP_000057330.1 UMP kinase -
  LTK19_RS13000 (LTK19_13000) frr 2580871..2581425 (+) 555 WP_001280006.1 ribosome recycling factor -
  LTK19_RS13005 (LTK19_13005) - 2581798..2582568 (+) 771 WP_000473705.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=549205 LTK19_RS12970 WP_000055337.1 2577048..2577821(+) (codY) [Staphylococcus aureus strain UNC_SaCF35]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=549205 LTK19_RS12970 WP_000055337.1 2577048..2577821(+) (codY) [Staphylococcus aureus strain UNC_SaCF35]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGCGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACACGATG
ACTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACAGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428