Detailed information NTG0549131

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: J4Q31_RS09715
• Genome accession: NZ_CP071918
• Coordinates: 1868761..1869798 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 19A-19343
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1863761..1874798

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4Q31_RS09690 (J4Q31_09690)	-	1864500..1865831 (-)	1332	WP_000390039.1	hemolysin family protein	-
J4Q31_RS09695 (J4Q31_09695)	endA	1866122..1866946 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
J4Q31_RS09700 (J4Q31_09700)	-	1866985..1867173 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
J4Q31_RS09705 (J4Q31_09705)	murA	1867166..1868449 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
J4Q31_RS09710 (J4Q31_09710)	-	1868473..1868703 (-)	231	WP_000615437.1	DUF1146 family protein	-
J4Q31_RS09715 (J4Q31_09715)	sepM	1868761..1869798 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
J4Q31_RS09720 (J4Q31_09720)	coaD	1869782..1870270 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
J4Q31_RS09725 (J4Q31_09725)	rsmD	1870260..1870799 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
J4Q31_RS09730 (J4Q31_09730)	asnA	1870864..1871856 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
J4Q31_RS09735 (J4Q31_09735)	-	1871968..1872651 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
J4Q31_RS09740 (J4Q31_09740)	-	1872707..1873447 (-)	741	WP_000152701.1	RNA methyltransferase	-
J4Q31_RS09745 (J4Q31_09745)	-	1873481..1873759 (+)	279	WP_001174613.1	acylphosphatase	-
J4Q31_RS09750 (J4Q31_09750)	yidC	1873837..1874763 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=549131 J4Q31_RS09715 WP_000727280.1 1868761..1869798(-) (sepM) [Streptococcus pneumoniae strain 19A-19343]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=549131 J4Q31_RS09715 WP_000727280.1 1868761..1869798(-) (sepM) [Streptococcus pneumoniae strain 19A-19343]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591