Detailed information NTG0548939

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: J4Q32_RS05785
• Genome accession: NZ_CP071916
• Coordinates: 1136426..1137379 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 19A-19087
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1131426..1142379

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4Q32_RS05760 (J4Q32_05760)	-	1131907..1132002 (-)	96	Protein_1154	IS630 family transposase	-
J4Q32_RS05765 (J4Q32_05765)	-	1132415..1132756 (+)	342	Protein_1155	transposase	-
J4Q32_RS05770 (J4Q32_05770)	prsA	1132873..1133814 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
J4Q32_RS05775 (J4Q32_05775)	-	1133881..1134594 (-)	714	WP_000230400.1	O-methyltransferase	-
J4Q32_RS05780 (J4Q32_05780)	pepF	1134596..1136407 (-)	1812	WP_000244158.1	oligoendopeptidase F	Regulator
J4Q32_RS05785 (J4Q32_05785)	coiA	1136426..1137379 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
J4Q32_RS05790 (J4Q32_05790)	tehB	1137452..1138312 (-)	861	WP_000413757.1	SAM-dependent methyltransferase TehB	-
J4Q32_RS05795 (J4Q32_05795)	smpB	1138328..1138795 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
J4Q32_RS05800 (J4Q32_05800)	rnr	1138758..1141112 (-)	2355	WP_000654886.1	ribonuclease R	-
J4Q32_RS05805 (J4Q32_05805)	secG	1141214..1141447 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
J4Q32_RS05810 (J4Q32_05810)	rpmG	1141487..1141636 (-)	150	WP_001810029.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=548939 J4Q32_RS05785 WP_000495909.1 1136426..1137379(-) (coiA) [Streptococcus pneumoniae strain 19A-19087]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=548939 J4Q32_RS05785 WP_000495909.1 1136426..1137379(-) (coiA) [Streptococcus pneumoniae strain 19A-19087]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435