Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   J4Q32_RS05780 Genome accession   NZ_CP071916
Coordinates   1134596..1136407 (-) Length   603 a.a.
NCBI ID   WP_000244158.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 19A-19087     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1129596..1141407
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4Q32_RS05745 (J4Q32_05745) - 1129710..1130552 (+) 843 WP_000954117.1 DUF368 domain-containing protein -
  J4Q32_RS05750 (J4Q32_05750) - 1130552..1131034 (+) 483 WP_001085888.1 aminoacyl-tRNA deacylase -
  J4Q32_RS05755 (J4Q32_05755) - 1131034..1131654 (+) 621 WP_000780813.1 histidine phosphatase family protein -
  J4Q32_RS05760 (J4Q32_05760) - 1131907..1132002 (-) 96 Protein_1154 IS630 family transposase -
  J4Q32_RS05765 (J4Q32_05765) - 1132415..1132756 (+) 342 Protein_1155 transposase -
  J4Q32_RS05770 (J4Q32_05770) prsA 1132873..1133814 (-) 942 WP_000727935.1 peptidylprolyl isomerase PrsA -
  J4Q32_RS05775 (J4Q32_05775) - 1133881..1134594 (-) 714 WP_000230400.1 O-methyltransferase -
  J4Q32_RS05780 (J4Q32_05780) pepF 1134596..1136407 (-) 1812 WP_000244158.1 oligoendopeptidase F Regulator
  J4Q32_RS05785 (J4Q32_05785) coiA 1136426..1137379 (-) 954 WP_000495909.1 competence protein CoiA Machinery gene
  J4Q32_RS05790 (J4Q32_05790) tehB 1137452..1138312 (-) 861 WP_000413757.1 SAM-dependent methyltransferase TehB -
  J4Q32_RS05795 (J4Q32_05795) smpB 1138328..1138795 (-) 468 WP_001051750.1 SsrA-binding protein SmpB -
  J4Q32_RS05800 (J4Q32_05800) rnr 1138758..1141112 (-) 2355 WP_000654886.1 ribonuclease R -

Sequence

Protein


Download         Length: 603 a.a.        Molecular weight: 70294.21 Da        Isoelectric Point: 4.5513

>NTDB_id=548938 J4Q32_RS05780 WP_000244158.1 1134596..1136407(-) (pepF) [Streptococcus pneumoniae strain 19A-19087]
MVLQRNERNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADNLLEITEFSLEMERQMEKLYVYAHM
KNDQDTREAKYQEYYAKAMTLYSQLDQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELL
AGAGEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQALYATYEQFQHTYAKTLQTNV
KVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQE
ALKKAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYT
RETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLT
SDFLNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSD
YPLNVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1812 bp        

>NTDB_id=548938 J4Q32_RS05780 WP_000244158.1 1134596..1136407(-) (pepF) [Streptococcus pneumoniae strain 19A-19087]
ATGGTATTACAAAGAAATGAAAGAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCA
GGCTTGGGAAGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCTTGGATAGTG
CGGATAACCTACTAGAAATCACTGAATTTTCTCTTGAAATGGAACGCCAGATGGAGAAGCTTTACGTTTATGCTCATATG
AAGAATGACCAGGATACACGTGAAGCTAAGTATCAAGAGTACTATGCCAAGGCCATGACACTCTACAGCCAGTTAGACCA
AGCCTTTTCATTCTATGATCCTGAATTTATGGAGATTAGCGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAACCAAAGC
TGCAGGTTTATCAACACTATTTTGACAAGCTCTTGCAAGGCAAGGATCACGTTCTTTCACAACGTGAAGAAGAATTATTG
GCTGGAGCTGGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGT
CCTAGACGATGATGGTAAAGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAAACGTGAGGTTC
GCCGTGGTGCCTATCAAGCTCTTTATGCGACTTACGAACAATTCCAACACACCTATGCCAAAACCTTGCAAACCAATGTT
AAGGTGCAAAATTACCGTGCTAAAGTTCGTAACTACAAGAGTGCTCGTCATGCAGCCCTCGCAGCGAATTTTGTTCCAGA
AAGTGTTTATGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTACATCGCTATCTTGAGCTTCGTTCAAAAA
TCTTGGGGATTTCAGATCTCAAGATGTACGATGTCTACACACCGCTTTCATCTGTTGAATACAATTTTACCTACCAAGAA
GCCTTGAAAAAAGCAGAAGATGCTTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTCAAACGTGCCTTCAGCGAGCG
TTGGATTGATGTTTACGAAAATCAAGGCAAGCGTTCAGGTGCCTACTCTGGTGGTTCTTACGATACCAATGCCTTTATGC
TTCTCAACTGGCAGGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCAAGCTATACT
CGTGAAACTCAGCCTTATGTTTACGGAGATTACTCTATCTTTTTGGCTGAGATTGCCTCAACTACCAATGAAAATATCTT
GACGGAGAAATTATTGGAAGAAGTGGAAGACGACGCAACACGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTG
GAACAGTTTTCCGCCAAACTCAATTTGCTGAGTTTGAACACGCCATTCACCAAGCAGATCAAAATGGGGAGGTCTTGACA
AGCGATTTCCTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCA
ATACGAGTGGGCTCGCATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACTGGCTTTGCGGCCGCCTCAG
CCTTGGCTGAAAAAATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAGTCGGAC
TATCCACTTAATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGCAGTCTTTGA
ACGCCGTTTAAATGAGTTTGAAGCCCTTGTTGAAAAATTAGGATTGGCATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(115-184)

Peptidase family M3 (Peptidase_M3)

(205-584)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.34

98.507

0.663