Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   K0768_RS12855 Genome accession   NZ_CP089142
Coordinates   1963737..1964393 (+) Length   218 a.a.
NCBI ID   WP_000611336.1    Uniprot ID   -
Organism   Escherichia coli strain XD35     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1958737..1969393
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K0768_RS12825 (LS330_12825) dcyD 1959616..1960602 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  K0768_RS12830 (LS330_12830) tcyL 1960617..1961285 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  K0768_RS12835 (LS330_12835) tcyN 1961282..1962034 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  K0768_RS12840 (LS330_12840) sdiA 1962264..1962986 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  K0768_RS12845 (LS330_12845) yecF 1963054..1963278 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  K0768_RS12850 (LS330_12850) yecU 1963265..1963441 (-) 177 WP_000590344.1 protein YecU -
  K0768_RS27065 - 1963479..1963595 (-) 117 Protein_1864 transcriptional regulator -
  K0768_RS12855 (LS330_12855) letA 1963737..1964393 (+) 657 WP_000611336.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  K0768_RS12860 (LS330_12860) uvrC 1964390..1966222 (+) 1833 WP_161997271.1 excinuclease ABC subunit UvrC Machinery gene
  K0768_RS12865 (LS330_12865) pgsA 1966279..1966827 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  K0768_RS12885 (LS330_12885) - 1967523..1968263 (-) 741 Protein_1868 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23878.58 Da        Isoelectric Point: 6.6397

>NTDB_id=548848 K0768_RS12855 WP_000611336.1 1963737..1964393(+) (letA) [Escherichia coli strain XD35]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITNGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=548848 K0768_RS12855 WP_000611336.1 1963737..1964393(+) (letA) [Escherichia coli strain XD35]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAATGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486