Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   JN057_RS02035 Genome accession   NZ_CP071871
Coordinates   379146..379835 (+) Length   229 a.a.
NCBI ID   WP_061370767.1    Uniprot ID   A0A4J1SXK8
Organism   Streptococcus pneumoniae strain BVJ1JL     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 374146..384835
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JN057_RS02010 (JN057_00426) gpsB 374255..374584 (+) 330 WP_000146522.1 cell division regulator GpsB -
  JN057_RS02020 (JN057_00428) - 375070..376227 (+) 1158 WP_000711391.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  JN057_RS02025 (JN057_00429) mapZ 376240..377634 (+) 1395 WP_000039273.1 cell division site-positioning protein MapZ -
  JN057_RS02030 (JN057_00430) gndA 377710..379134 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  JN057_RS02035 (JN057_00431) covR 379146..379835 (+) 690 WP_061370767.1 response regulator transcription factor Regulator
  JN057_RS02040 (JN057_00432) cbpC 379933..380952 (+) 1020 WP_000771110.1 choline-binding protein CbpC -
  JN057_RS02045 (JN057_00433) - 381070..382302 (-) 1233 WP_000765670.1 MFS transporter -
  JN057_RS02050 (JN057_00434) - 382462..382932 (-) 471 WP_001844742.1 lanthionine synthetase LanC family protein -
  JN057_RS11735 - 382832..383170 (-) 339 Protein_408 lanthionine synthetase LanC family protein -
  JN057_RS02060 - 384040..384162 (+) 123 Protein_409 cell wall-binding protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26884.19 Da        Isoelectric Point: 6.9835

>NTDB_id=548601 JN057_RS02035 WP_061370767.1 379146..379835(+) (covR) [Streptococcus pneumoniae strain BVJ1JL]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEDLEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=548601 JN057_RS02035 WP_061370767.1 379146..379835(+) (covR) [Streptococcus pneumoniae strain BVJ1JL]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGATCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4J1SXK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463