Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   JZ789_RS09160 Genome accession   NZ_CP071806
Coordinates   1817474..1818163 (-) Length   229 a.a.
NCBI ID   WP_002942700.1    Uniprot ID   A0A126UNE5
Organism   Streptococcus suis strain GX69     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1812474..1823163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZ789_RS09135 (JZ789_09050) - 1812791..1813504 (-) 714 WP_029175276.1 NADPH-dependent oxidoreductase -
  JZ789_RS09140 (JZ789_09055) dnaI 1813501..1814400 (-) 900 WP_024382411.1 primosomal protein DnaI -
  JZ789_RS09145 (JZ789_09060) - 1814400..1815551 (-) 1152 WP_170244827.1 replication initiation/membrane attachment protein -
  JZ789_RS09150 (JZ789_09065) nrdR 1815538..1816029 (-) 492 WP_024417739.1 transcriptional regulator NrdR -
  JZ789_RS09155 (JZ789_09070) - 1816101..1817231 (-) 1131 WP_002942701.1 AI-2E family transporter -
  JZ789_RS09160 (JZ789_09075) covR 1817474..1818163 (-) 690 WP_002942700.1 DNA-binding response regulator Regulator
  JZ789_RS09165 (JZ789_09080) gndA 1818245..1819672 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  JZ789_RS09170 (JZ789_09085) - 1819760..1820299 (-) 540 WP_024417740.1 DUF177 domain-containing protein -
  JZ789_RS09175 (JZ789_09090) trxB 1820309..1821226 (-) 918 WP_024417741.1 thioredoxin-disulfide reductase -
  JZ789_RS09180 (JZ789_09095) - 1821240..1821464 (-) 225 WP_024417742.1 DUF4059 family protein -
  JZ789_RS09185 (JZ789_09100) - 1821482..1822825 (-) 1344 WP_024380515.1 DEAD/DEAH box helicase -
  JZ789_RS09190 (JZ789_09105) - 1822905..1823159 (-) 255 WP_226313349.1 PTS lactose transporter subunit IIB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26225.11 Da        Isoelectric Point: 5.3968

>NTDB_id=547966 JZ789_RS09160 WP_002942700.1 1817474..1818163(-) (covR) [Streptococcus suis strain GX69]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=547966 JZ789_RS09160 WP_002942700.1 1817474..1818163(-) (covR) [Streptococcus suis strain GX69]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTTTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGACTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UNE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432