Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   J3S98_RS06690 Genome accession   NZ_CP071729
Coordinates   1317260..1318732 (+) Length   490 a.a.
NCBI ID   WP_063283897.1    Uniprot ID   -
Organism   Lactococcus cremoris strain FM-YL11     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1312260..1323732
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J3S98_RS06660 (J3S98_06660) - 1312727..1313563 (+) 837 WP_021165524.1 metallophosphoesterase -
  J3S98_RS06665 (J3S98_06665) - 1313656..1314567 (+) 912 Protein_1288 CHAP domain-containing protein -
  J3S98_RS06670 (J3S98_06670) - 1314804..1315166 (+) 363 Protein_1289 TIGR02328 family protein -
  J3S98_RS06675 (J3S98_06675) - 1315490..1315735 (+) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  J3S98_RS06680 (J3S98_06680) - 1315868..1316398 (+) 531 WP_011834860.1 DUF177 domain-containing protein -
  J3S98_RS06685 (J3S98_06685) covR 1316555..1317247 (+) 693 WP_011676631.1 response regulator transcription factor Regulator
  J3S98_RS06690 (J3S98_06690) covS 1317260..1318732 (+) 1473 WP_063283897.1 HAMP domain-containing histidine kinase Regulator
  J3S98_RS06695 (J3S98_06695) - 1318918..1320159 (+) 1242 WP_015082643.1 ammonium transporter -
  J3S98_RS06700 (J3S98_06700) - 1320244..1320585 (+) 342 WP_011676628.1 P-II family nitrogen regulator -
  J3S98_RS06705 (J3S98_06705) murD 1320754..1322103 (+) 1350 WP_021165520.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  J3S98_RS06710 (J3S98_06710) murG 1322346..1323419 (+) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55872.71 Da        Isoelectric Point: 4.7011

>NTDB_id=547307 J3S98_RS06690 WP_063283897.1 1317260..1318732(+) (covS) [Lactococcus cremoris strain FM-YL11]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRRDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNHWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKI

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=547307 J3S98_RS06690 WP_063283897.1 1317260..1318732(+) (covS) [Lactococcus cremoris strain FM-YL11]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACGTGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
ATTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCCAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTGGCTCGTTTAGCCGAAAATTATCAAGGAGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATATGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.49

100

0.945