Detailed information NTG0546822

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: J3R87_RS14205
• Genome accession: NZ_CP071594
• Coordinates: 2840697..2841740 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain PNID0137
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2835697..2846740

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J3R87_RS14175 (J3R87_14175)	-	2836118..2837374 (-)	1257	WP_001793983.1	aminopeptidase	-
J3R87_RS14180 (J3R87_14180)	-	2837377..2837577 (-)	201	WP_000180460.1	DUF1128 family protein	-
J3R87_RS14185 (J3R87_14185)	-	2837724..2838188 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
J3R87_RS14190 (J3R87_14190)	-	2838195..2838470 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
J3R87_RS14195 (J3R87_14195)	-	2838748..2839965 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
J3R87_RS14200 (J3R87_14200)	vraR	2840078..2840707 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
J3R87_RS14205 (J3R87_14205)	vraS	2840697..2841740 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
J3R87_RS14210 (J3R87_14210)	liaF	2841737..2842438 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
J3R87_RS14215 (J3R87_14215)	-	2842453..2842839 (-)	387	WP_001110178.1	hypothetical protein	-
J3R87_RS14220 (J3R87_14220)	map	2843056..2843814 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
J3R87_RS14225 (J3R87_14225)	-	2844400..2845386 (+)	987	WP_001014423.1	aromatic acid exporter family protein	-
J3R87_RS14230 (J3R87_14230)	-	2845575..2845988 (-)	414	WP_001643743.1	hypothetical protein	-
J3R87_RS14235 (J3R87_14235)	-	2846017..2846127 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=546822 J3R87_RS14205 WP_001017131.1 2840697..2841740(-) (vraS) [Staphylococcus aureus strain PNID0137]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=546822 J3R87_RS14205 WP_001017131.1 2840697..2841740(-) (vraS) [Staphylococcus aureus strain PNID0137]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1