Detailed information NTG0546011

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: J2N86_RS10525
• Genome accession: NZ_CP071527
• Coordinates: 2391445..2394183 (+)
• Length: 912 a.a.
• NCBI ID: WP_252579393.1
• Uniprot ID: -
• Organism: Legionella lytica strain PCM 2298
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2386445..2399183

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J2N86_RS10505 (J2N86_10515)	gstA	2386599..2387201 (-)	603	WP_252579387.1	glutathione transferase GstA	-
J2N86_RS10510 (J2N86_10520)	-	2387223..2388233 (-)	1011	WP_252579388.1	hypothetical protein	-
J2N86_RS10515 (J2N86_10525)	-	2388352..2389611 (-)	1260	WP_407658991.1	serine hydrolase domain-containing protein	-
J2N86_RS10520 (J2N86_10530)	gltX	2389843..2391258 (-)	1416	WP_252579391.1	glutamate--tRNA ligase	-
J2N86_RS10525 (J2N86_10535)	letS	2391445..2394183 (+)	2739	WP_252579393.1	two-component system sensor histidine kinase LetS	Regulator
J2N86_RS10530 (J2N86_10540)	-	2394386..2395621 (+)	1236	WP_252579394.1	6-phosphofructokinase	-
J2N86_RS10535 (J2N86_10545)	pilA2	2395694..2396125 (+)	432	WP_252579396.1	pilin	Machinery gene
J2N86_RS10540 (J2N86_10550)	-	2396127..2396441 (+)	315	WP_252579397.1	BolA family transcriptional regulator	-
J2N86_RS10545 (J2N86_10555)	-	2396539..2397276 (-)	738	WP_252579398.1	outer membrane protein	-
J2N86_RS10550 (J2N86_10560)	-	2397389..2399101 (-)	1713	WP_252579399.1	S8 family serine peptidase	-

Sequence

Protein

• Length: 912 a.a.
• Molecular weight: 102915.91 Da
• Isoelectric Point: 6.8608

>NTDB_id=546011 J2N86_RS10525 WP_252579393.1 2391445..2394183(+) (letS) [Legionella lytica strain PCM 2298]
MKSIGIKYQLRITTLIPAFLVALLFAVFYNGLFGNDLKQHMSRLGEAYIRQLVPAAQYAMLRRDDRTLQGLINASTINPE
VKALAFYNSEGQLLAYRGGKHSIHKPFTPPDFTGDYIESKQINPFTINFIAPVTIPKFNLYSNNTFSKNLTNASAFQADD
ILGWLSIDIDTRSMLIKRYQMLIVTIFITLFGLLMGLTSHYFLSKRIYLPISRLRRSMKQILRNEFETEIKTTSKGELGI
IEKGCAHLQKKYIDTIKDLNQHIEVATEDLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQMDYVKTIKSSAQDLLGIINDILDFSKIDAGKLHLDCIPLNIRHCIDEVLTLAAPTAHKKGIDLIPITD
INVPKTVLGDPFRIKQFISNLITNAVKFTDHGYVLIRTHIEQETEKDYTLCITISDTGLGISPEDQSKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMGGRLSMTSELNKGSAFTAHIKVEKLAAYEIEKNQTHRFAHFKVLCFDDNPLHLEALCNG
LGYWGIECISVSSFSQLSQALDDNIDCKMAFVNVNQGCERQMEKIIAAHNHFPYVLISKWHIHDYAALGAHGFLFKPISI
QKLQDIIELLINESPQKKQGNHELDGLREQLRFLHPDLLIAEDNPVNKMLLDSLLGTHANIDAVDDGEMAVSSCNEKKYD
IILLDLQMPKLNGLDAARIIRQKSQLNRHTPVVLISANSSDVNNTELKKSGINLCLQKPIDEKQLLMHILRIVDRAKHAA
IDWQLCVQKVSGNQELAEEFLRQFVEELHKNREEFIDLMHNKDIKQLGAAAHKLHGACCFSGVPTLQAKVIQVEKMAARP
ASIDELAIPFAELIQSIDAVISEYENLPEKNT

Nucleotide

• Length: 2739 bp

>NTDB_id=546011 J2N86_RS10525 WP_252579393.1 2391445..2394183(+) (letS) [Legionella lytica strain PCM 2298]
TTGAAAAGTATTGGTATCAAATATCAGCTAAGAATTACCACCCTTATCCCAGCCTTTCTCGTCGCCTTGCTCTTCGCAGT
CTTTTATAATGGCCTCTTTGGTAATGACCTAAAACAGCACATGTCACGCCTTGGAGAAGCCTATATTCGCCAATTAGTAC
CCGCAGCTCAGTATGCCATGCTTCGTCGAGATGATCGCACCTTACAAGGCTTAATTAATGCCTCAACAATTAACCCTGAG
GTTAAAGCACTCGCGTTTTATAATAGCGAAGGACAACTCCTGGCCTATCGCGGCGGGAAGCATTCAATACATAAACCCTT
TACGCCACCTGATTTCACAGGGGATTATATTGAAAGCAAGCAAATAAATCCCTTCACTATTAATTTCATTGCCCCTGTCA
CTATTCCTAAATTTAATCTGTACTCTAATAACACTTTTAGTAAAAACCTAACGAATGCTTCAGCCTTTCAAGCCGATGAT
ATCCTTGGTTGGCTCTCTATTGATATTGATACACGTTCTATGTTGATCAAACGTTATCAAATGCTGATTGTTACTATTTT
CATTACCTTATTTGGTTTGCTAATGGGGCTAACCAGCCATTATTTTCTCTCAAAACGTATTTATTTACCCATTTCGCGCT
TGCGTCGTAGCATGAAACAAATTCTACGTAACGAATTTGAAACCGAAATAAAAACCACCAGTAAAGGTGAGTTAGGTATT
ATTGAAAAAGGATGCGCCCATTTACAAAAAAAATACATCGATACAATTAAAGACCTTAATCAACATATTGAAGTCGCGAC
CGAAGATTTACAGCAAAGTCTGGAGCTTTTAGAAGAAAAAAATATTGAACTGTCTTTAGAAAAGAAAAAAACTGAAGAAA
AAAGCCGGCAAAAATCTGAGTTTATTGCCAATATGAGCCACGAGATTCGTACGCCAATGAATGGAGTCATTGGTTTTACT
AATGTGTTATTGGAAAGTAAACTTGACCCACTACAAATGGATTATGTCAAAACCATTAAATCCTCTGCTCAAGATTTATT
AGGTATTATTAATGACATCCTCGACTTCTCAAAAATTGATGCAGGAAAATTGCATCTGGATTGCATTCCCTTAAATATCC
GGCATTGTATTGATGAGGTACTTACTTTAGCGGCTCCTACAGCTCATAAGAAAGGAATTGATTTAATTCCGATTACCGAC
ATTAACGTACCCAAAACGGTATTAGGCGACCCCTTCCGTATTAAACAATTCATCAGTAATCTAATAACCAATGCCGTAAA
GTTTACGGATCATGGCTATGTGCTTATCCGAACGCACATCGAACAAGAAACAGAAAAAGATTACACCCTGTGCATTACGA
TCAGTGATACGGGATTAGGAATATCCCCGGAGGATCAAAGCAAACTATTTACTGCATTTAATCAGGCCGATACGAGCATT
ACTCGCCGTTACGGGGGCTCTGGTTTAGGGCTAGTCATTTGTAAAAAGCTTTGTGAAGAAATGGGTGGTCGTTTGAGCAT
GACCAGTGAGCTCAACAAGGGCTCGGCTTTTACTGCTCATATCAAAGTGGAAAAACTAGCTGCTTATGAAATAGAAAAAA
ATCAAACACATCGCTTTGCTCATTTTAAAGTCTTGTGCTTCGATGATAATCCTCTGCATTTGGAAGCCTTATGTAATGGC
TTAGGTTATTGGGGAATTGAATGTATCTCCGTGAGTTCATTTAGTCAGCTGTCTCAAGCCCTAGATGATAATATAGACTG
TAAAATGGCCTTCGTGAACGTAAACCAAGGCTGTGAACGGCAAATGGAAAAAATTATTGCTGCCCATAATCATTTCCCCT
ACGTACTTATTTCCAAATGGCATATTCATGATTATGCGGCATTAGGGGCACATGGCTTTTTATTTAAACCCATTAGTATC
CAAAAACTGCAAGATATTATTGAATTACTCATTAACGAAAGCCCTCAAAAAAAACAAGGGAATCATGAATTAGATGGCTT
ACGAGAACAATTACGTTTTCTGCATCCAGACTTGTTAATTGCTGAAGATAATCCTGTAAATAAAATGCTATTGGATTCAT
TGTTAGGAACCCATGCTAACATCGATGCGGTAGACGATGGGGAAATGGCTGTTTCCTCATGTAATGAAAAAAAATACGAT
ATTATCCTGCTTGATTTGCAAATGCCGAAGCTAAATGGTTTAGATGCAGCACGAATCATTCGTCAAAAATCCCAACTCAA
CCGACATACACCGGTAGTTTTGATTAGCGCCAATAGCAGTGATGTCAATAATACGGAGTTAAAGAAATCAGGCATAAATC
TTTGCCTGCAAAAGCCCATTGATGAAAAGCAATTATTGATGCATATTCTACGTATTGTTGATAGAGCCAAACATGCTGCT
ATTGATTGGCAACTCTGCGTACAAAAAGTTTCAGGAAACCAAGAGCTTGCAGAAGAATTTTTACGCCAATTTGTTGAAGA
GCTGCATAAAAATCGTGAAGAATTTATCGATCTCATGCACAACAAAGACATCAAACAACTTGGCGCTGCAGCACATAAGC
TTCATGGAGCCTGTTGCTTTTCCGGAGTGCCTACCTTACAAGCGAAGGTAATCCAGGTAGAAAAGATGGCCGCGCGCCCC
GCCTCTATTGACGAACTCGCCATTCCCTTTGCCGAATTAATTCAAAGTATTGATGCGGTAATTAGCGAGTATGAAAATCT
ACCCGAAAAAAATACTTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (679-788)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Single cache domain 4 (sCache_4) (35-180)

• Hpt domain (Hpt) (819-899)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	79.801	99.342	0.793