Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LN359_RS10970 Genome accession   NZ_CP087377
Coordinates   2268334..2268990 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C019217     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2263334..2273990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LN359_RS10940 (LN359_10945) dcyD 2264214..2265200 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  LN359_RS10945 (LN359_10950) tcyL 2265215..2265883 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  LN359_RS10950 (LN359_10955) tcyN 2265880..2266632 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LN359_RS10955 (LN359_10960) sdiA 2266862..2267584 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  LN359_RS10960 (LN359_10965) yecF 2267651..2267875 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  LN359_RS10965 (LN359_10970) yecU 2267862..2268038 (-) 177 WP_000590347.1 protein YecU -
  LN359_RS10970 (LN359_10975) letA 2268334..2268990 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LN359_RS10975 (LN359_10980) uvrC 2268987..2270819 (+) 1833 WP_001551272.1 excinuclease ABC subunit UvrC Machinery gene
  LN359_RS10980 (LN359_10985) pgsA 2270876..2271424 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LN359_RS11000 (LN359_11005) yecA 2272074..2272739 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=545868 LN359_RS10970 WP_000611328.1 2268334..2268990(+) (letA) [Escherichia coli strain RIVM_C019217]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=545868 LN359_RS10970 WP_000611328.1 2268334..2268990(+) (letA) [Escherichia coli strain RIVM_C019217]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482